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Iatrogenic botulism in a child with spastic quadriparesis
- Source :
- Journal of child neurology. 22(10)
- Publication Year :
- 2007
-
Abstract
- Botulinum toxins are potent neurotoxins used in a variety of neurological disorders. Few pediatric reports have been published to date regarding the potential hazards of therapeutic use of botulinum toxins. We describe the case of a 10-year-old boy who developed systemic weakness following treatment of spasticity with botulinum toxin type B. The patient developed iatrogenic botulism with ptosis, facial diplegia, neck flexor and extensor weakness, and profound hypopharyngeal laxity with respiratory compromise from which he eventually recovered. Clinicians should be mindful of the risk for systemic botulism when using local injections of the neurotoxin.
- Subjects :
- Male
Weakness
Botulinum Toxins
Iatrogenic Disease
Quadriplegia
03 medical and health sciences
0302 clinical medicine
Sleep Apnea Syndromes
Ptosis
medicine
Neurotoxin
Humans
Botulism
Spasticity
Botulinum Toxins, Type A
030223 otorhinolaryngology
Adverse effect
Child
Muscle, Skeletal
Muscle Weakness
business.industry
Pharyngeal Diseases
Recovery of Function
medicine.disease
Botulinum toxin
Anesthesia
Pediatrics, Perinatology and Child Health
Disease Progression
Neurology (clinical)
medicine.symptom
Iatrogenic Botulism
Laryngeal Muscles
business
Respiratory Insufficiency
030217 neurology & neurosurgery
medicine.drug
Subjects
Details
- ISSN :
- 08830738
- Volume :
- 22
- Issue :
- 10
- Database :
- OpenAIRE
- Journal :
- Journal of child neurology
- Accession number :
- edsair.doi.dedup.....29248f5255b1152969a326fd69435d09