Supplementary Figure 4 from SHP2 Inhibition Overcomes RTK-Mediated Pathway Reactivation in KRAS-Mutant Tumors Treated with MEK Inhibitors

Authors :: Huai-Xiang Hao
Morvarid Mohseni
Giordano Caponigro
Peter S. Hammerman
Jeffrey A. Engelman
Susan E. Moody
Saskia M. Brachmann
Eusebio Manchado
Eric Billy
Anne Haberkorn
Malika Kazic-Legueux
Lukas Manuel Dunkl
Hongyun Wang
Roberto Velazquez
Chen Liu
Hengyu Lu
Publication Year :: 2023
Publisher :: American Association for Cancer Research (AACR), 2023.
Abstract: Evaluation of the in vivo combination benefit and the MAPK pathway suppression of MEK and SHP2 inhibitors in MIA PaCa-2 xenograft and a colon cancer PDX model.

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