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Gd-EOB-DTPA-Enhanced MRI is Better than MDCT in Decision Making of Curative Treatment for Hepatocellular Carcinoma
- Source :
- Annals of Surgical Oncology. 20:2893-2900
- Publication Year :
- 2013
- Publisher :
- Springer Science and Business Media LLC, 2013.
-
Abstract
- We assessed the change in the therapeutic decision among curative treatments after adding Gd-EOB-DTPA-enhanced MRI to triple-phase MDCT for patients with early-stage HCC. This study retrospectively investigated two groups: 33 pathologically confirmed HCC patients after liver transplantation in group 1; 34 HCC patients without pathology in group 2. In group 1, we simulated the therapeutic decision-making process by pretransplant MDCT and Gd-EOB-DTPA-enhanced MRI. In group 2, including the 34 early-stage HCC patients consecutively enrolled, we investigated the change of therapeutic decision after adding Gd-EOB-DTPA-enhanced MRI to MDCT. In the simulation from group 1, after adding Gd-EOB-DTPA-enhanced MRI, 33.3 % (11/33 patients) of treatment decisions were changed from the decision based on MDCT alone. Among 22 patients considered eligible for resection and 33 patients for radiofrequency ablation, the therapeutic decision was changed for 10 patients in the surgical group and 4 patients for the RFA group (45.5 and 12.1 %). In group 2, the rate of change in the therapeutic decision after adding Gd-EOB-DTPA-enhanced MRI to MDCT was 41.2 % (14/34 patients). In group 1 with explants pathology, the median diameter of HCCs not detected by MDCT but detected by Gd-EOB-DTPA-enhanced MRI was 1.15 cm (0.3–3.0 cm). The median diameter of HCCs seen only in the explanted liver was 1.0 cm (0.3–1.7 cm), and 60.7 % of them were well-differentiated HCCs. This study suggests that performing Gd-EOB-DTPA-enhanced MRI before deciding on curative treatment for early-stage HCC may improve the accuracy of treatment decision for early-stage HCC.
- Subjects :
- Gadolinium DTPA
Male
medicine.medical_specialty
Carcinoma, Hepatocellular
Radiofrequency ablation
medicine.medical_treatment
Decision Making
Contrast Media
Liver transplantation
law.invention
Text mining
Surgical oncology
law
Multidetector Computed Tomography
medicine
Carcinoma
Humans
cardiovascular diseases
Neoplasm Staging
Retrospective Studies
medicine.diagnostic_test
business.industry
Liver Neoplasms
Magnetic resonance imaging
Retrospective cohort study
Middle Aged
Prognosis
medicine.disease
Magnetic Resonance Imaging
Oncology
Hepatocellular carcinoma
cardiovascular system
Female
Surgery
Radiology
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 15344681 and 10689265
- Volume :
- 20
- Database :
- OpenAIRE
- Journal :
- Annals of Surgical Oncology
- Accession number :
- edsair.doi.dedup.....28a650e85d0814473e833d872bf9d13d