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Predicting In-depth mechanisms of action for cancer drugs

Authors :
Sanju Sinha
Publication Year :
2022
Publisher :
Zenodo, 2022.

Abstract

Data for "Predicting In-depth mechanisms of action for cancer drugs." Please download these files and put them in a folder named "Data". Download the respective scripts from https://github.com/ruppinlab/drug.OnTarget<br />File Description: onTarget (onTarget_v3.0.RDS): A single object is a curation of all the DepMap data including viability screens after CRISPR-Cas9 & drug treatment, expression & mutation of cell lines. KnowTraget_prediction (KnownTarget_predictions_v4.RDS): Metadata of Drugs and their target+DeepTarget's top predicted target information drugVScrispr_corr_features_list (drugVScrispr_corr_features_list.RDS): DKS Score & P for each gene vs each drug. drugVScrispr_corr_features_list_secondary (drugVScrispr_corr_features_list_secondary.RDS): Secondary DKS Score & P for each gene vs each drug.

Subjects

Subjects :
Source Data

Details

Language :
English
Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....28917f7672645c024ebd4b058c4e8d50
Full Text :
https://doi.org/10.5281/zenodo.7407156