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An Individual-Based Model of Transmission of Resistant Bacteria in a Veterinary Teaching Hospital
- Source :
- PLoS ONE, PLoS ONE, Vol 9, Iss 6, p e98589 (2014)
- Publication Year :
- 2014
- Publisher :
- Public Library of Science (PLoS), 2014.
-
Abstract
- Veterinary nosocomial infections caused by antibiotic resistant bacteria cause increased morbidity, higher cost and length of treatment and increased zoonotic risk because of the difficulty in treating them. In this study, an individual-based model was developed to investigate the effects of movements of canine patients among ten areas (transmission points) within a veterinary teaching hospital, and the effects of these movements on transmission of antibiotic susceptible and resistant pathogens. The model simulates contamination of transmission points, healthcare workers, and patients as well as the effects of decontamination of transmission points, disinfection of healthcare workers, and antibiotic treatments of canine patients. The model was parameterized using data obtained from hospital records, information obtained by interviews with hospital staff, and the published literature. The model suggested that transmission resulting from contact with healthcare workers was common, and that certain transmission points (housing wards, diagnostics room, and the intensive care unit) presented higher risk for transmission than others (lobby and surgery). Sensitivity analyses using a range of parameter values demonstrated that the risk of acquisition of colonization by resistant pathogens decreased with shorter patient hospital stays (P
- Subjects :
- Veterinary Medicine
Veterinary medicine
medicine.medical_specialty
medicine.drug_class
media_common.quotation_subject
Veterinary Microbiology
Antibiotics
lcsh:Medicine
Population Modeling
Veterinary Epidemiology
law.invention
Teaching hospital
Hospitals, Animal
Antibiotic resistance
Hygiene
law
Drug Resistance, Bacterial
Health care
Medicine and Health Sciences
Animals
Medicine
lcsh:Science
Hospitals, Teaching
Intensive care medicine
media_common
Cross Infection
Multidisciplinary
business.industry
lcsh:R
Biology and Life Sciences
Computational Biology
Bacterial Infections
Intensive care unit
Anti-Bacterial Agents
Resistant bacteria
Infectious Diseases
Transmission (mechanics)
Veterinary Diseases
Veterinary Informatics
lcsh:Q
Veterinary Science
Infectious Disease Modeling
business
Veterinary Pathology
Research Article
Subjects
Details
- ISSN :
- 19326203
- Volume :
- 9
- Database :
- OpenAIRE
- Journal :
- PLoS ONE
- Accession number :
- edsair.doi.dedup.....27f6b605a5bdf0c5d87ccd24c8bd74bc