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Supplementary Figure 3. from A Pilot Trial of Humanized Anti-GD2 Monoclonal Antibody (hu14.18K322A) with Chemotherapy and Natural Killer Cells in Children with Recurrent/Refractory Neuroblastoma

Authors :
Wayne L. Furman
Alberto S. Pappo
Victor M. Santana
Rachel C. Brennan
Shenghua Mao
Jianrong Wu
William E. Janssen
Wing Leung
Catherine Y. Ng
Aaron Shafer
Michael Meagher
Paul Hutson
Jacquelyn A. Hank
Paul M. Sondel
Barry L. Shulkin
M. Beth McCarville
Sara M. Federico
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

The left panel plots the calculated area under the concentration vs time curve (AUC) of hu14.18K322A and the right panel plots the highest observed serum concentration of hu14.18K322A (Cmax) against the pre-treatment concentration of HAHA antibodies, reported in units of optical density. There is no clear association between the concentration of HAHA at the start of treatment and the AUC of hu14.18K322A and the peak concentration of hu14.18K322A using the Spearman test.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....27cf4fb5f2122705d1133af93245a8ae
Full Text :
https://doi.org/10.1158/1078-0432.22468172