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Figure S2 from CD19/CD20 Bispecific Chimeric Antigen Receptor (CAR) in Naive/Memory T Cells for the Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma

Authors :
Yvonne Y. Chen
Antoni Ribas
John M. Timmerman
Gary J. Schiller
Caspian Oliai
Patricia A. Young
Sven de Vos
Monica Mead
Karla Nawaly
Jonathan Said
Martin S. Allen-Auerbach
Melanie Ayala Ceja
Amr Almaktari
Stanley B. Gosliner
Beata Berent-Maoz
Thomas Schweppe
Mobina Khericha
Caitlin Harris
Mobina Roshandell
Jia Ming Chen
Jacqueline Trent
Jacob Naparstek
Sanaz N. Ghafouri
Brenda Ji
Christopher M. Walthers
Sarah M. Larson
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

CD14/CD20 depletion did not significantly alter regulatory T (Treg) cell content in CART19/20 cell product and in patient peripheral blood post infusion. Intracellular staining of starting (unactivated) TN/MEM population, CART19/20 final product, and patient PBMC collected 14 days post CART19/20 infusion. FOXP3+ frequency is shown as a percentage of CD3+CD4+ T cells.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....27ce7104fa04f8ded469f3da9cb11620
Full Text :
https://doi.org/10.1158/2159-8290.22542540