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The great fall of chloroquine- lessons learned from the pandemic

Authors :
null Binu Krishnan
Publication Year :
2022
Publisher :
Zenodo, 2022.

Abstract

Drugs like chloroquine (CQ)/ Hydroxy chloroquine (HCQ) had been widely used as treatment options at the start of pandemic with little supporting evidence. American Thoracic Society (ATS) led International Task Force had come up with some important `suggestions’ regarding CQ/ HCQ usage initially. They have suggested to use these drugs in covid 19 patients with severe pneumonia on a case by case basis. However, the role of HCQ prophylaxis, the effect of combination with macrolides, benefit versus risk assessment, age group profile and the exact definition of severe pneumonia remain unanswered among others. Now, it had become quite obvious that our perceptions based on some observational studies were completely wrong.

Details

Language :
English
Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....27b5acbd63d64448c6386cab06a9a36f
Full Text :
https://doi.org/10.5281/zenodo.6844709