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Suboptimal response to GnRHa long protocol is associated with a common LH polymorphism
- Source :
- Università degli studi di Salerno-IRIS, Aarhus University, Alviggi, C, Clarizia, R, Pettersson, K, Mollo, A, Al Humaidan, P S H, Strina, I, Coppola, M, Ranieri, A, D'Uva, M & De Placido, G 2009, ' Suboptimal response to GnRHa long protocol is associated with a common LH polymorphism ', RBM Online, vol. 18, no. 1, pp. 9-14 ., Alviggi, C, Clarizia, R, Pettersson, K, Mollo, A, Al Humaidan, P S H, Strina, I, Coppola, M, Ranieri, A, D'Uva, M & De Placido, G 2011, ' Suboptimal response to GnRHa long protocol is associated with a common LH polymorphism ', RBM Online, vol. 22 Suppl 1, pp. S67-72 . https://doi.org/10.1016/S1472-6483(11)60011-4, Alviggi, C, Clarizia, R, Pettersson, K, Mollo, A, Humaidan, P, Strina, I, Coppola, M, Ranieri, A, D'Uva, M & De Placido, G 2011, ' Suboptimal response to GnRHa long protocol is associated with a common LH polymorphism ', Reproductive BioMedicine Online, vol. 22, no. Suppl 1, pp. S67-72 . https://doi.org/10.1016/S1472-6483(11)60011-4
- Publication Year :
- 2009
-
Abstract
- The aim of this observational preliminary trial was to estimate the association between the most common polymorphism of LH (LH-beta variant: v-betaLH), with different profiles of ovarian response to recombinant human FSH (rhFSH). A total of 60 normogonadotrophic patients undergoing a gonadotrophin-releasing hormone analogue long down-regulation protocol followed by stimulation with recombinant human FSH (rhFSH) for IVF/intracytoplasmic sperm injection, and in whom at least five oocytes were retrieved were retrospectively included. On the basis of the total rhFSH consumption, patients were divided into three groups: Group A: 22 women requiring a cumulative dose of rhFSH >3500 IU; Group B: 15 patients requiring 2000-3500 IU; Group C (control): 23 women requiring
- Subjects :
- Adult
Ovulation
medicine.medical_specialty
media_common.quotation_subject
medicine.medical_treatment
Drug Resistance
Fertilization in Vitro
Biology
Group A
Polymorphism, Single Nucleotide
Group B
Intracytoplasmic sperm injection
Gonadotropin-Releasing Hormone
Young Adult
Gene Frequency
Ovulation Induction
Polymorphism (computer science)
Pregnancy
Internal medicine
medicine
Humans
media_common
Retrospective Studies
Clinical Trials as Topic
Estradiol
Cumulative dose
Obstetrics and Gynecology
Luteinizing Hormone
Recombinant Proteins
Endocrinology
Reproductive Medicine
Amino Acid Substitution
Ovulation induction
Female
Luteinizing hormone
Developmental Biology
Subjects
Details
- ISSN :
- 14726491
- Volume :
- 18
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Reproductive biomedicine online
- Accession number :
- edsair.doi.dedup.....27b4a2e44105ae76904c23f6b5d018fe