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The significance of heart failure in hospitalised patients with pulmonary embolism. A gender‐specific analysis
- Source :
- E-Prints Complutense. Archivo Institucional de la UCM, instname, International Journal of Clinical Practice, r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- Background: Heart failure (HF) is a risk factor for the development of pulmonary embolism (PE). Few studies have examined sex differences in risk of PE among HF patients. Aims: (a) To examine the incidence, characteristics and in-hospital outcomes among patients hospitalised with PE according to HF status; (b) to compare the in-hospital mortality (IHM) after PE between HF and non-HF patients and (c) to identify variables associated with IHM. All analyses were stratified by sex. Methods: We included all adult patients hospitalised for PE from 1 January 2016 to 31 December 2018. Data were collected from the Spanish National Hospital Discharge Database. Poisson regression models were constructed to quantify the difference in the incidences between HF and non-HF populations. Propensity score matching (PSM) was used to obtain comparable subgroups by sex and HF status. Results: We identified 46,835 PE hospitalisations, 11.4% with HF. Adjusted incidence of PE was higher in HF patients than in those without HF (Incidence Rate Ratio 1.11; 95% CI 1.08-1.13). Crude and PSM adjusted IHM were significantly higher in men and women hospitalised with PE suffering HF than in men and women without HF (P < .001). Women with HF who suffered a PE had lower IHM than men with this condition (P < .001) after adjusting. Conclusions: Adjusted incidence of PE was higher in HF patients than in those without HF. After PSM suffering, HF was associated to higher IHM in men and women. Women with PE and HF had lower IHM than men with these conditions.
- Subjects :
- Adult
Male
medicine.medical_specialty
Cardiología
Rate ratio
symbols.namesake
Risk Factors
Internal medicine
Humans
Medicine
Hospital Mortality
Poisson regression
Risk factor
Neumología
Retrospective Studies
Heart Failure
business.industry
Incidence
Incidence (epidemiology)
Hospital discharge database
General Medicine
medicine.disease
Pulmonary embolism
Spain
Heart failure
Propensity score matching
symbols
Female
Pulmonary Embolism
business
Subjects
Details
- Language :
- English
- ISSN :
- 13685031
- Database :
- OpenAIRE
- Journal :
- E-Prints Complutense. Archivo Institucional de la UCM, instname, International Journal of Clinical Practice, r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
- Accession number :
- edsair.doi.dedup.....2774cad2b672d76726c731158b065116