Altered closed state inactivation gating in Kv4.2 channels results in developmental and epileptic encephalopathies in human patients

Authors :: Selvan Bavan
Howard P. Goodkin
Diane M. Papazian
Source :: Human mutationREFERENCES. 43(9)
Publication Year :: 2022
Abstract: Kv4.2 subunits, encoded by KCND2, serve as the pore-forming components of voltage-gated, inactivating I

Subjects :: Male
Kinetics
Shal Potassium Channels
Mutation
Genetics
Humans
Epilepsy, Generalized
Ion Channel Gating
Genetics (clinical)

Tools