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Crystallographic and spectroscopic characterization of 2-[(7-acetyl-4-cyano-6-hydroxy-1,6-dimethyl-8-phenyl-5,6,7,8-tetrahydroisoquinolin-3-yl)sulfanyl]-N-phenylacetamide
- Source :
- Acta Crystallographica Section E: Crystallographic Communications, Acta Crystallographica Section E: Crystallographic Communications, Vol 77, Iss 2, Pp 121-125 (2021)
- Publication Year :
- 2021
- Publisher :
- International Union of Crystallography (IUCr), 2021.
-
Abstract
- The heterocyclic portion of the tetra­hydro­iso­quinoline unit is planar and an intra­molecular N—H⋯N hydrogen bond and a C—H⋯π(ring) inter­action help to determine the overall conformation. In the crystal, O—H⋯O hydrogen bonds form inversion dimers, which are connected by C—H⋯O hydrogen bonds, forming layers parallel to (10).<br />In the title mol­ecule, C28H27N3O3S, the heterocyclic portion of the tetra­hydro­iso­quinoline unit is planar and an intra­molecular N—H⋯N hydrogen bond and a C—H⋯π(ring) inter­action help to determine the overall conformation. In the crystal, a layer structure with the layers parallel to (10) is generated by O—H⋯O and C—H⋯O hydrogen bonds.
- Subjects :
- crystal structure
phenylacetamide
phenylacetamide
Crystal structure
010402 general chemistry
010403 inorganic & nuclear chemistry
Ring (chemistry)
01 natural sciences
Medicinal chemistry
Research Communications
Crystal
chemistry.chemical_compound
c—h...π(ring) interaction
General Materials Science
Quantitative Biology::Biomolecules
hydrogen bond
Crystallography
biology
Hydrogen bond
Chemistry
Tetrahydroisoquinoline
General Chemistry
Condensed Matter Physics
biology.organism_classification
0104 chemical sciences
tetrahydroisoquinoline
QD901-999
Tetra
C—H⋯π(ring) interaction
tetrahydroisoquinoline
Acetamide
Subjects
Details
- ISSN :
- 20569890
- Volume :
- 77
- Database :
- OpenAIRE
- Journal :
- Acta Crystallographica Section E Crystallographic Communications
- Accession number :
- edsair.doi.dedup.....274036253360413fbb54e081f6a473fe