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Crystallographic and spectroscopic characterization of 2-[(7-acetyl-4-cyano-6-hydroxy-1,6-dimethyl-8-phenyl-5,6,7,8-tetrahydroisoquinolin-3-yl)sulfanyl]-N-phenylacetamide

Authors :
Shaaban K. Mohamed
Etify A. Bakhite
Islam S. Maraei
Güneş Demirtaş
Joel T. Mague
Elham A. Al-Taifi
Youssef Ramli
Source :
Acta Crystallographica Section E: Crystallographic Communications, Acta Crystallographica Section E: Crystallographic Communications, Vol 77, Iss 2, Pp 121-125 (2021)
Publication Year :
2021
Publisher :
International Union of Crystallography (IUCr), 2021.

Abstract

The heterocyclic portion of the tetra­hydro­iso­quinoline unit is planar and an intra­molecular N—H⋯N hydrogen bond and a C—H⋯π(ring) inter­action help to determine the overall conformation. In the crystal, O—H⋯O hydrogen bonds form inversion dimers, which are connected by C—H⋯O hydrogen bonds, forming layers parallel to (10).<br />In the title mol­ecule, C28H27N3O3S, the heterocyclic portion of the tetra­hydro­iso­quinoline unit is planar and an intra­molecular N—H⋯N hydrogen bond and a C—H⋯π(ring) inter­action help to determine the overall conformation. In the crystal, a layer structure with the layers parallel to (10) is generated by O—H⋯O and C—H⋯O hydrogen bonds.

Details

ISSN :
20569890
Volume :
77
Database :
OpenAIRE
Journal :
Acta Crystallographica Section E Crystallographic Communications
Accession number :
edsair.doi.dedup.....274036253360413fbb54e081f6a473fe