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Two-voxel localization sequence for in vivo two-dimensional homonuclear correlation spectroscopy
- Source :
- Journal of Magnetic Resonance, 149(1), 119-125. ACADEMIC PRESS INC ELSEVIER SCIENCE, Journal of Magnetic Resonance, 149(1), 119-125. Academic Press Inc.
- Publication Year :
- 2001
-
Abstract
- The combination of localized 2D 1H MR correlation spectroscopy and Hadamard encoding allows the simultaneous acquisition of multiple volumes of interest without an increase in the experimental duration, compared to single-voxel acquisition. In the present study, 2D correlation spectra were acquired simultaneously within 20 to 40 min in two voxels located in each hemisphere of the rat brain. An intervoxel distance of 20% of the voxel size was sufficient to limit spatial contamination. The following cerebral metabolites gave detectable crosspeaks: N-acetylaspartate, the glutamate/glutamine pool, aspartate, phosphoethanolamine, glucose, glutathione, taurine, myo-inositols, lactate, threonine, ¿-aminobutyric acid, and alanine. Most of the metabolites were measured without contamination of other resonances. two-dimensional correlation 1H MRS
- Subjects :
- multivoxel localization
Nuclear and High Energy Physics
Magnetic Resonance Spectroscopy
Biophysics
Hadamard encoding
RAT-BRAIN
PROTON
computer.software_genre
METABOLITES
LACTATE
Biochemistry
Aminobutyric acid
Homonuclear molecule
Brain Ischemia
Nuclear magnetic resonance
Reference Values
In vivo
Voxel
rat brain
Image Processing, Computer-Assisted
Animals
Lactic Acid
Threonine
Dominance, Cerebral
IN-VIVO
Alanine
Phantoms, Imaging
Chemistry
Brain
RADIOFREQUENCY PULSES
two-dimensional correlation H-1 MRS
Image Enhancement
Condensed Matter Physics
Magnetic Resonance Imaging
Rats
RF PULSES
Glutamine
PHOSPHORUS
NMR-SPECTROSCOPY
cerebral metabolites
Brain Damage, Chronic
Energy Metabolism
1D-HADAMARD
computer
Two-dimensional nuclear magnetic resonance spectroscopy
Subjects
Details
- Language :
- English
- ISSN :
- 10907807
- Volume :
- 149
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Journal of Magnetic Resonance
- Accession number :
- edsair.doi.dedup.....273bf8665594d40bdb3d0b164b071aed