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Right ventricular outflow tract reconstruction with the Labcor® stentless valved pulmonary conduit
- Source :
- European Journal of Cardio-Thoracic Surgery.
- Publication Year :
- 2019
- Publisher :
- Oxford University Press (OUP), 2019.
-
Abstract
- OBJECTIVES The right ventricular outflow tract reconstruction is a common necessity in congenital cardiac surgery. As homograft availability is limited, alternatives need to be evaluated. The Labcor® conduit consists of a porcine tricomposite valve assembled inside a bovine pericardium tube. This study presents intermediate-term results for its utilization for right ventricular outflow tract reconstruction. METHODS Labcor conduits were implanted in 53 patients (February 2009–July 2016). We analysed perioperative data, freedom from conduit failure and risk factors for conduit dysfunction. RESULTS The most common diagnosis was Tetralogy of Fallot (n = 20, 37.7%). The median age at surgery was 10.0 [interquartile range (IQR) 4.9–14.3] years. Pulmonary artery plasty (n = 37, 69.8%) and augmentation of the right ventricular outflow tract (n = 16, 30.2%) were often part of the procedure. The median conduit size was 21 (range 11–25) mm. There was no in-hospital death. The median follow-up after surgery was 4.6 (IQR 3.4–5.6) years. Fourteen patients (27.5%) developed conduit failure with stenosis being the main cause. Freedom from conduit failure was 98.0% at 2 and 80.5% at 5 years. The median longevity of the conduit was 7.4 years (95% confidence interval 5.1–9.8 years). Younger age and smaller conduit size were related to conduit failure. CONCLUSIONS Utilization of the Labcor conduit revealed acceptable intermediate-term results. The conduit appeared to be functioning sufficiently well within the first 5 years in the majority of patients. The higher rate of failure concerning smaller conduits might be associated with somatic outgrowth; however, conduit degeneration as common and long-term outcome still needs to be evaluated.
- Subjects :
- Heart Defects, Congenital
Reoperation
Pulmonary and Respiratory Medicine
medicine.medical_specialty
Adolescent
Swine
Heart Ventricles
610 Medicine & health
030204 cardiovascular system & hematology
2705 Cardiology and Cardiovascular Medicine
Ventricular Outflow Obstruction
03 medical and health sciences
0302 clinical medicine
Electrical conduit
Interquartile range
medicine.artery
medicine
Animals
Humans
Ventricular outflow tract
cardiovascular diseases
Child
Retrospective Studies
Tetralogy of Fallot
Bioprosthesis
business.industry
Infant
General Medicine
Perioperative
medicine.disease
2746 Surgery
Cardiac surgery
Surgery
Stenosis
Treatment Outcome
10036 Medical Clinic
2740 Pulmonary and Respiratory Medicine
Child, Preschool
Heart Valve Prosthesis
030220 oncology & carcinogenesis
Pulmonary artery
cardiovascular system
Cattle
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- ISSN :
- 1873734X and 10107940
- Database :
- OpenAIRE
- Journal :
- European Journal of Cardio-Thoracic Surgery
- Accession number :
- edsair.doi.dedup.....2730c594f6d6d10069832c0e71b7d203
- Full Text :
- https://doi.org/10.1093/ejcts/ezz200