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Changes in gentamicin pharmacokinetics after reduction of renal parenchyma
- Source :
- Experientia. 33:1075-1076
- Publication Year :
- 1977
- Publisher :
- Springer Science and Business Media LLC, 1977.
-
Abstract
- The relationship between the elimination constant of gentamicin and the percentage of functioning nephrons in rats cannot be characterized by a simple linear relation. The results support the assumption that gentamicin elimination per residual nephron increased.
- Subjects :
- medicine.medical_specialty
Renal parenchyma
Urology
Nephron
Kidney
urologic and male genital diseases
Nephrectomy
Cellular and Molecular Neuroscience
Elimination rate constant
Pharmacokinetics
medicine
Animals
Molecular Biology
Pharmacology
urogenital system
Chemistry
Cell Biology
Rats
Surgery
medicine.anatomical_structure
Linear relation
Molecular Medicine
Female
Gentamicin
Gentamicins
medicine.drug
Subjects
Details
- ISSN :
- 14209071 and 00144754
- Volume :
- 33
- Database :
- OpenAIRE
- Journal :
- Experientia
- Accession number :
- edsair.doi.dedup.....2717c5867f074a4232de6fb7a4f3095e
- Full Text :
- https://doi.org/10.1007/bf01945978