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Changes in gentamicin pharmacokinetics after reduction of renal parenchyma

Authors :
Hatala M
Morávek J
Schück O
Source :
Experientia. 33:1075-1076
Publication Year :
1977
Publisher :
Springer Science and Business Media LLC, 1977.

Abstract

The relationship between the elimination constant of gentamicin and the percentage of functioning nephrons in rats cannot be characterized by a simple linear relation. The results support the assumption that gentamicin elimination per residual nephron increased.

Details

ISSN :
14209071 and 00144754
Volume :
33
Database :
OpenAIRE
Journal :
Experientia
Accession number :
edsair.doi.dedup.....2717c5867f074a4232de6fb7a4f3095e
Full Text :
https://doi.org/10.1007/bf01945978