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Retrospective 15-Year Review of Anal Cytology Screening in Women at Mayo Clinic Rochester, Minnesota
- Source :
- Journal of Lower Genital Tract Disease. 24:238-242
- Publication Year :
- 2020
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2020.
-
Abstract
- Objectives Anal cytology is a modality for anal cancer screening in high-risk women. In this retrospective study, we review risk factors associated with abnormal anal cytology and unsatisfactory anal cytology rates, and correlate findings of cytology with histological results. Methods A retrospective cohort study of anal cytology screening in women at Mayo Clinic in Rochester, Minnesota from 2002 to 2018 was conducted. Results Three hundred fifty-seven women had a total of 592 anal cytologies performed. Three hundred seventeen women had screening anal cytology, whereas 40 women had anal cytology for surveillance given a history of anal intraepithelial neoplasia (AIN) or anal cancer. An unsatisfactory anal cytology result was found in 14.7%. Risk factors, type of follow-up, and correlation with histologic specimens were also reviewed. Histologic finding of AIN 2/3 correlated with abnormal anal cytology 84% of the time in this cohort. Conclusions High-risk women should be screened on a periodic basis for anal cancer. Anal cytology is one possible modality that can be used. Further insight into AIN progression, regression, recurrence, and outcome after treatment will help direct future screening recommendations.
- Subjects :
- Adult
medicine.medical_specialty
Cytological Techniques
Anal Canal
03 medical and health sciences
0302 clinical medicine
Risk Factors
Cytology
medicine
Humans
Anal cancer
Early Detection of Cancer
Retrospective Studies
030219 obstetrics & reproductive medicine
business.industry
Obstetrics
Anal intraepithelial neoplasia
Obstetrics and Gynecology
Retrospective cohort study
General Medicine
Middle Aged
Anus Neoplasms
medicine.disease
Anal cytology
030220 oncology & carcinogenesis
Cohort
Female
business
Carcinoma in Situ
After treatment
Subjects
Details
- ISSN :
- 15260976
- Volume :
- 24
- Database :
- OpenAIRE
- Journal :
- Journal of Lower Genital Tract Disease
- Accession number :
- edsair.doi.dedup.....26aad5a54472f9caf36c1e8a91d6a9b1