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Genome Sequence of an Emerging Salmonella enterica Serovar Infantis and Genomic Comparison with Other S. Infantis Strains
- Source :
- Genome Biology and Evolution
- Publication Year :
- 2020
-
Abstract
- Salmonella enterica serovar Infantis (S. Infantis) is one of the dominant serovars of the bacterial pathogen S. enterica. In recent years, the number of human infections caused by S. Infantis has been increasing in many countries, and often the emerging population harbors a unique virulence-resistant megaplasmid called plasmid of emerging S. Infantis (pESI). Here, we report the complete gap-free genome sequence of the S. Infantis Israeli emerging clone and compare its chromosome and pESI sequences with other complete S. Infantis genomes. We show a conserved presence of the Salmonella pathogenicity islands 1–6, 9, 11, 12, and CS54 and a common integration of five bacteriophages in the S. Infantis chromosome. In contrast, we found variable presence of additionally three chromosomally integrated phages and eight modular regions in pESI, which contribute to the genetic and phenotypic diversity (including antimicrobial resistance) of this ubiquitous foodborne pathogen.
- Subjects :
- Serotype
Salmonella
Genomic Islands
Population
Biology
medicine.disease_cause
Genome
03 medical and health sciences
Genetics
medicine
education
Ecology, Evolution, Behavior and Systematics
030304 developmental biology
Whole genome sequencing
0303 health sciences
education.field_of_study
030306 microbiology
Salmonella enterica
Salmonella Infantis
HGT
mobile genetic elements
Genomics
biology.organism_classification
Pathogenicity island
Genome Report
virulence
pESI
Mobile genetic elements
Genome, Bacterial
WGS
Plasmids
Subjects
Details
- ISSN :
- 17596653
- Volume :
- 12
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Genome biology and evolution
- Accession number :
- edsair.doi.dedup.....268a7a26272c490357daafdab82fa362