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Cell transformation by light charged particles: review of available data
- Source :
- Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 73
- Publication Year :
- 2005
-
Abstract
- Summary Data reported in the literature on neoplastic transformation induced in cultured cells by light charged particles are compared and analyzed as a function of LET and dose protraction. Light charged particles RBE for transformation is maximum between 75 and 120 keV/μm . The majority of the data suggest that RBE values for survival and transformation are of similar magnitude. Dose protraction effects on transformation induction depend on dose, dose rate and on radiation quality.
- Subjects :
- Radiation quality
Summary data
Cell
Mice
medicine
Relative biological effectiveness
Animals
Radiology, Nuclear Medicine and imaging
Neoplastic transformation
Linear Energy Transfer
Mice, Inbred C3H
business.industry
Chemistry
Dose-Response Relationship, Radiation
Hematology
Alpha Particles
Charged particle
Transformation (genetics)
medicine.anatomical_structure
Cell Transformation, Neoplastic
Oncology
Biophysics
Dose Fractionation, Radiation
Protons
Nuclear medicine
business
Dose rate
Relative Biological Effectiveness
Subjects
Details
- ISSN :
- 01678140
- Volume :
- 73
- Database :
- OpenAIRE
- Journal :
- Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
- Accession number :
- edsair.doi.dedup.....261b669716b8adc2cb6021a558c373a8