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Isolation, characterization and antimicrobial activities of polyacetylene glycosides from Coreopsis tinctoria Nutt
- Source :
- Phytochemistry. 136:65-69
- Publication Year :
- 2017
- Publisher :
- Elsevier BV, 2017.
-
Abstract
- Polyacetylene glycosides, (6Z, 12E)-tetradecadiene-8,10-diyne-1-ol-3(R)-O-β-D-glucopyranoside (trivially named coreoside E) and (6Z, 12E)-tetradecadiene-8,10-diyne-1-ol-3(R)-O-β-L-arabinopyranosyl-(1 → 2)-β-D-glucopyranoside (trivially named coreoside F), were isolated from buds of Coreopsis tinctoria Nutt., together with one known compound, coreoside B. Their chemical structures were elucidated by extensive spectroscopic analysis and on the basis of their chemical reactivities. Coreoside E exhibited high levels of antimicrobial activity against Staphylococcus aureus and Bacillus anthracis with minimum inhibitory concentrations of 27 ± 0.27 and 18 ± 0.40 μM, respectively, whereas coreoside F and coreoside B showed weak antimicrobial activity against S. aureus and B. anthracis.
- Subjects :
- Staphylococcus aureus
Stereochemistry
Microbial Sensitivity Tests
Plant Science
Horticulture
medicine.disease_cause
01 natural sciences
Biochemistry
Polyacetylene
chemistry.chemical_compound
Anti-Infective Agents
Glucosides
Botany
medicine
Glycosides
Molecular Biology
chemistry.chemical_classification
Molecular Structure
biology
010405 organic chemistry
Polyynes
Glycoside
General Medicine
Asteraceae
Antimicrobial
biology.organism_classification
0104 chemical sciences
Bacillus anthracis
Coreopsis
010404 medicinal & biomolecular chemistry
chemistry
Coreoside F
Subjects
Details
- ISSN :
- 00319422
- Volume :
- 136
- Database :
- OpenAIRE
- Journal :
- Phytochemistry
- Accession number :
- edsair.doi.dedup.....260b6b1610b5bd6352220e1f08cbac27