Daily Fasting Effect on Weight Reduction, Diabetes, and Cravings in GLOBESITY Bootcamp for the Obese

(research summary) 14 hours a day fasting reduces weight up to 3.2 kg, total cholesterol by 7%, low-density lipoprotein (LDL) cholesterol by 11%, and non-high-density lipoprotein (HDL) by 9% in 12 weeks (Wilkinson et al., 2019). 14 hours a day fasting improves fasting glucose by 5%, fasting insulin by 21%, and HbA1c by 2% in 12 weeks (Wilkinson et al., 2019). Short-term fasting increases metabolic rate by 3.6% to 14%, helping to burn additional calories (Mansell, 1990; Zauner, 2000). Three weeks of fasting nearly completely abolishes reactivity to food images and the frequency of cravings. This effect is much stronger for individuals who include fasting as part of their dietary regimen, as opposed to diet alone (Lappalainen, 1990).
{"references":["Wilkinson, M. J., Manoogian, E. N. C., Zadourian, A., Lo, H., Fakhouri, S., Shoghi, A., … Taub, P. R. (2019). Ten-Hour Time-Restricted Eating Reduces Weight, Blood Pressure, and Atherogenic Lipids in Patients with Metabolic Syndrome. Cell Metabolism. doi:10.1016/j.cmet.2019.11.004","Barnosky, A., Hoddy, K., Unterman, T., et al. (2014). Intermittent fasting vs daily calorie restriction for type 2 diabetes prevention: a review of human findings. Translational Research [online], 164 (4), pp. 302-11.","Blackman, M., Sorkin, J., Munzer, T., et al. (2002). Growth hormone and sex steroid administration in healthy aged women and men: a randomized controlled trial. Journal of American Medical Association [online], 288 (18), pp. 2282-92.","Chaix, A., Zarrinpar, A., Miu, P., et al. (2014). Time-restricted feeding is a preventative and therapeutic intervention against diverse nutritional challenges. Cell Metabolism [online], 20(6), pp. 991-1005.","from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255155/ [Accessed 25.05.2016]. Hallack. M., Nomani, M. (1988). Body weight loss and changes in blood lipid levels in normal men on hypocaloric diets during Ramadan fasting. The American Journal of Clinical Nutrition [online], 48 (5), pp. 1997-210.","Hartman, M., Veldhuis, J., Johnson, M., et al. (1992). Augmented growth hormone (GH) secretory burst frequency and amplitude mediate enhanced GH secretion during a two-day fast in normal men. Journal of Endocrinology and Metabolism [online], 74 (4), pp. 756-65.","Harvie, M., Pegington, M., Mattson, M., et al. (2011). The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women. International Journal of Obesity [online], 35 (5), pp. 714-27.","Heilbronn, L., Smith, S., Martin, C., et al. (2005). Alternate-day fasting in nonobese subjects: effects on body weight, body composition, and energy metabolism. American Journal of Clinical Nutrition [online], 81 (1), pp. 69-73.","Ho, K., Veldhuis, J., Johnson, M., et al. (1988). Fasting enhances growth hormone secretion and amplifies the complex rhythms of growth hormone secretion in man. Journal of Clinical Investigation [online], 81 (4), pp. 968-75.","Johnstone, A. (2007). Fasting? The Ultimate Diet?. Obesity Reviews [online], 8 (3), pp. 211-22.","Lappalainen, R., Sjödén, P.O., Hursti, T., Vesa, V. (1990). Hunger/craving responses and reactivity to food stimuli during fasting and dieting. International Journal of Obesity [online], 14 (8), pp. 679-88.","Mansell, P., Fellows, I., Macdonald, I. (1990). Enhanced thermogenic response to epinephrine after 48-h starvation in humans. The American Journal of Physiology [online], 258 (1), pp. 87-93.","Rudman, D., Feller, A., Nagraj, H., et al. (1990). Effects of human growth hormone in men over 60 years old. The New England Journal of Medicine [online], 323 (1), pp. 1-6.","Wilcox, G. (2005). Insulin and Insulin Resistance. Clinical Biochemical Review [online]; 26 (2), pp. 19–39.","Zauner, C., Schneeweiss, B., Kranz, A., et al. (2000). Resting energy expenditure in short-term starvation is increased as a result of an increase in serum norepinephrine. The American Journal of Clinical Nutrition [online], 71 (6), pp. 1511-5"]}