Effects of third ventricle injection of protaglandins on gonadotropin secretion in goldfish Carassius auratus

Authors :: R.E. Peter
R. Billard
Department of Zoology
Auburn University (AU)
UR 0544 JOUY GENETIQUE DES POISSONS Unité de recherche Génétique des Poissons. Centre de recherche Jouy-en-Josas
Institut National de la Recherche Agronomique (INRA)
Laboratoire de physiologie des poissons
Source :: General and Comparative Endocrinology, General and Comparative Endocrinology, Elsevier, 1976, 30, pp.451-456. ⟨10.1016/0016-6480(76)90114-3⟩
Publication Year :: 1976
Publisher :: HAL CCSD, 1976.
Abstract: The effects of injection of prostaglandin (PG) E1, PGE2, and PGF2? into the third ventricle on serum gonadotropin (GTH) concentrations in the goldfish were tested. Blood samples were taken at 30 min postinjection for radioimmunoassay of serum GTH. PG dosages of 0.5 and 1.0 ?g were ineffective. However, PGE2 and PGF2? at the 2.0-?g dosage significantly suppressed serum GTH. PGE1 at a 2.0-?g dosage had no effect. There were no effects on serum GTH when 2.0 ?g of PGE1, PGE2, or PGF2? were injected intraperitoneally. The results indicate that PGE2 and PGF2? suppress gonadotropin secretion by some action, presumably on the hypothalamus. However, action of PGE2 and PGF2? by diffusion from the site of injection to some other brain site or the pituitary cannot be eliminated in the present study.

Language :: English
ISSN :: 00166480 and 10956840
Database :: OpenAIRE
Journal :: General and Comparative Endocrinology, General and Comparative Endocrinology, Elsevier, 1976, 30, pp.451-456. ⟨10.1016/0016-6480(76)90114-3⟩
Accession number :: edsair.doi.dedup.....25dda96522442d047fede3cc1f00852e
Full Text :: https://doi.org/10.1016/0016-6480(76)90114-3⟩

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