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Modular Analysis and Design of Biological Circuits
- Source :
- MIT web domain
- Publication Year :
- 2019
-
Abstract
- Modularity has been the subject of intense investigation in systems biology for more than two decades. Whether modularity holds in biological networks is a question that has attracted renewed attention in recent years with the advent of synthetic biology, mostly as a convenient property to perform bottom-up design of complex systems. A number of studies have appeared, which fundamentally challenge modularity as a property of engineered biological circuits. Here, we summarize some of these studies and potential engineering solutions that have been proposed to enable modular composition of biological circuits. ©2019 Elsevier Ltd.<br />NSF through CMMI (Award no. 1727189)
- Subjects :
- 0106 biological sciences
0303 health sciences
Modularity (networks)
Property (philosophy)
Computer science
business.industry
Systems biology
Systems Biology
Biomedical Engineering
Complex system
Bioengineering
Synthetic biological circuit
Modular design
01 natural sciences
03 medical and health sciences
Synthetic biology
010608 biotechnology
Systems engineering
Synthetic Biology
business
Biological network
030304 developmental biology
Biotechnology
Subjects
Details
- ISSN :
- 18790429
- Volume :
- 63
- Database :
- OpenAIRE
- Journal :
- Current opinion in biotechnology
- Accession number :
- edsair.doi.dedup.....25d0623b10ff866580dfbb7268be1c6f