Improvement of the functional capacity is associated with BDNF and autonomic modulation in Chagas disease

35%) [2] must be considered. The power of these findings are limited by thesmall numberof patientswithmoderate airways reversibility (n=4). However,we take some reassurance from the goodproportionof patients diagnosed with asthma recruited to the study. Despite the limitation, we believe our study provides important hypothesis-generating data that contributes to a paucity of relevant literature in this area. A larger long-term study is required to provide definitive data regarding the effect of nebivolol on CHF patients withmoderate reversibility airways disease.