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Fast Contrast-Enhanced 4D MRA and 4D Flow MRI Using Constrained Reconstruction (HYPRFlow): Potential Applications for Brain Arteriovenous Malformations
- Source :
- American Journal of Neuroradiology. 36:1049-1055
- Publication Year :
- 2015
- Publisher :
- American Society of Neuroradiology (ASNR), 2015.
-
Abstract
- HYPRFlow is a novel imaging strategy that provides fast, high-resolution contrast-enhanced time-resolved images and measurement of the velocity of the entire cerebrovascular system. Our hypothesis was that the images obtained with this strategy are of adequate diagnostic image quality to delineate the major components of AVMs.HYPRFlow and 3D TOF scans were obtained in 21 patients with AVMs with correlative DSA examinations in 14 patients. The examinations were scored for image quality and graded by using the Spetzler-Martin criteria. Mean arterial transit time and overlap integrals were calculated from the dynamic image data. Volume flow rates in normal arteries and AVM feeding arteries were measured from the phase contrast data.HYPRFlow was equivalent to 3D-TOF in delineating normal arterial anatomy, arterial feeders, and nidus size and was concordant with DSA for AVM grading and venous drainage in 13 of the 14 examinations. Mean arterial transit time on the AVM side was 0.49 seconds, and on the normal contralateral side, 2.53 seconds with P.001. Across all 21 subjects, the mean arterial volume flow rate in the M1 segment ipsilateral to the AVM was 4.07 ± 3.04 mL/s; on the contralateral M1 segment, it was 2.09 ± 0.64 mL/s. The mean volume flow rate in the largest feeding artery to the AVM was 3.86 ± 2.74 mL/s.HYPRFlow provides an alternative approach to the MRA evaluation of AVMs, with the advantages of increased coverage, 0.75-second temporal resolution, 0.68-mm isotropic spatial resolution, and quantitative measurement of flow in 6 minutes.
- Subjects :
- Adult
Intracranial Arteriovenous Malformations
Male
medicine.medical_specialty
Image quality
Neuroimaging
Article
Magnetic resonance angiography
Humans
Medicine
Radiology, Nuclear Medicine and imaging
Image resolution
Aged
medicine.diagnostic_test
business.industry
Angiography, Digital Subtraction
Magnetic resonance imaging
Magnetic Resonance Imaging
Temporal resolution
Angiography
Female
Neurology (clinical)
Radiology
business
Nuclear medicine
Magnetic Resonance Angiography
Subjects
Details
- ISSN :
- 1936959X and 01956108
- Volume :
- 36
- Database :
- OpenAIRE
- Journal :
- American Journal of Neuroradiology
- Accession number :
- edsair.doi.dedup.....259ecd68e75a536d996bbfb9bd86d0f7