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Oncoplastic Repair in Breast Conservation: Comprehensive Evaluation of Techniques and Oncologic Outcomes of 937 Patients
- Source :
- Clinical breast cancer. 20(6)
- Publication Year :
- 2020
-
Abstract
- Background Breast-conserving surgery, especially with oncoplastic breast surgery (OBS), is becoming the standard of care in the surgical management of breast cancer. We investigated the applied technique of OBS and oncologic outcomes in a large series of patients. Patients and Methods This study was conducted between January 2008 and June 2018 in two centers in Iran. Patients underwent OBS. Early and late postoperative complications, oncologic outcomes, and follow-up data were documented. Results Nine hundred thirty-seven patients with a mean ± standard deviation age of 48.1 ± 11.3 underwent OBS. Most of the patients were diagnosed with early-stage disease, of which the most common pathology was invasive ductal carcinoma (83.3%). Lateral oncoplasty was the most commonly used OBS technique (324 cases, 34.6%). The most common complication was seroma formation. Reduction-type OBS technique had the highest rate of complications (13.1%). Thirty-four patients (5.4%) experienced local recurrence, with a median recurrence time of 26.4 months. Nine patients (1.3%) died from cancer recurrence. Conclusion OBS is a safe procedure with minor complications and good oncologic outcomes. These techniques can be applied to most patients who are candidates for breast-conserving surgery.
- Subjects :
- 0301 basic medicine
Adult
Reoperation
Cancer Research
medicine.medical_specialty
Standard of care
Breast surgery
medicine.medical_treatment
Mammaplasty
Breast Neoplasms
Iran
Mastectomy, Segmental
Cancer recurrence
Disease-Free Survival
03 medical and health sciences
0302 clinical medicine
Breast cancer
Postoperative Complications
Medicine
Humans
Breast
Prospective Studies
Neoplasm Staging
Retrospective Studies
Breast conservation
business.industry
Large series
Margins of Excision
Middle Aged
medicine.disease
Neoadjuvant Therapy
Surgery
030104 developmental biology
Oncology
Chemotherapy, Adjuvant
030220 oncology & carcinogenesis
Seroma
Female
Neoplasm Recurrence, Local
business
Complication
Follow-Up Studies
Subjects
Details
- ISSN :
- 19380666
- Volume :
- 20
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Clinical breast cancer
- Accession number :
- edsair.doi.dedup.....2596d5f07eeeede708525c6213ff7595