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Cognitive function assessed by Mini-mental state examination and risk of all-cause mortality: a community-based prospective cohort study
- Source :
- BMC Geriatrics, BMC Geriatrics, Vol 21, Iss 1, Pp 1-10 (2021)
- Publication Year :
- 2021
- Publisher :
- BioMed Central, 2021.
-
Abstract
- Background The Mini-Mental State Examination (MMSE) is the most widely used instrument to test cognitive functioning. The present study prospectively investigated the association between MMSE scores, MMSE domains, and all-cause mortality. Methods A total of 2134 participants aged 60 years or over, selected from one urban community-dwelling population in China, were enrolled in the study. The cognitive test was performed by use of the MMSE at baseline, and covariates were recorded simultaneously. Cox regression models were used for examining the cognitive function, expressed by different MMSE transformations, and all-cause mortality. After followed up for a median of 10.8 years (ranging from 1.0 to 11.3 years), loss to follow-up was 13.1% and 1854 individuals were finally included in the analyses. Results The subjects had the mean (SD) age of 71.01 (7.00) years, and 754 (40.67%) of them were women. Per point increase on MMSE scores was associated a 4% decreased risk of all-cause mortality [hazard ratio (HR): 0.96; 95%confidence interval (CI): 0.93–0.98]; compared to MMSE scores of ≥24, MMSE scores of Conclusion Cognitive impairment is associated with the increased risk of all-cause mortality in the Chinese elderly. Similarly, reduced MMSE scores, as well as impaired MMSE domains, are also associated with the increasing risk of all-cause mortality.
- Subjects :
- medicine.medical_specialty
Population
Neuropsychological Tests
Cognition
Elderly
Internal medicine
medicine
Humans
Cognitive Dysfunction
Prospective Studies
Mortality
education
Prospective cohort study
Mini-mental state examination
Aged
education.field_of_study
Mini–Mental State Examination
medicine.diagnostic_test
Proportional hazards model
business.industry
Research
Hazard ratio
RC952-954.6
Mental Status and Dementia Tests
Cognitive test
Geriatrics
Female
Geriatrics and Gerontology
business
All cause mortality
Subjects
Details
- Language :
- English
- ISSN :
- 14712318
- Volume :
- 21
- Database :
- OpenAIRE
- Journal :
- BMC Geriatrics
- Accession number :
- edsair.doi.dedup.....255356dbbb301a9c0d14ff8f651dbf26