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Pulling out the 1%:whole-genome capture for the targeted enrichment of ancient DNA sequencing libraries

Authors :
Nikola Theodossiev
Cristina Valdiosera
Simon Gravel
Diana Dimitrova
Yingrui Li
Krasimir Leshtakov
M. Thomas P. Gilbert
William J. Greenleaf
Martin Sikora
Andrés Moreno-Estrada
Meredith L. Carpenter
Morten E. Allentoft
Sonia Guillén
Hannes Schroeder
Eske Willerslev
Georgi Nekhrizov
Karla Sandoval
Jason D. Buenrostro
Morten Rasmussen
Jun Wang
Davide Pettener
Carlos Bustamante
Donata Luiselli
Carpenter ML
Buenrostro JD
Valdiosera C
Schroeder H
Allentoft ME
Sikora M
Rasmussen M
Gravel S
Guillén S
Nekhrizov G
Leshtakov K
Dimitrova D
Theodossiev N
Pettener D
Luiselli D
Sandoval K
Moreno-Estrada A
Li Y
Wang J
Gilbert MT
Willerslev E
Greenleaf WJ
Bustamante CD.
Source :
Carpenter, M L, Buenrostro, J D, Valdiosera Morales, C, Schroeder, H, Allentoft, M E, Sikora, M, Rasmussen, M, Gravel, S, Guillén, S, Nekhrizov, G, Leshtakov, K, Dimitrova, D, Theodossiev, N, Pettener, D, Luiselli, D, Sandoval, K, Moreno-Estrada, A, Li, Y, Wang, J, Gilbert, T, Willerslev, E, Greenleaf, W J & Bustamante, C D 2013, ' Pulling out the 1% : whole-genome capture for the targeted enrichment of ancient DNA sequencing libraries ', American Journal of Human Genetics, vol. 93, no. 5, pp. 852-864 . https://doi.org/10.1016/j.ajhg.2013.10.002
Publication Year :
2013

Abstract

Most ancient specimens contain very low levels of endogenous DNA, precluding the shotgun sequencing of many interesting samples because of cost. Ancient DNA (aDNA) libraries often contain

Details

Language :
English
Database :
OpenAIRE
Journal :
Carpenter, M L, Buenrostro, J D, Valdiosera Morales, C, Schroeder, H, Allentoft, M E, Sikora, M, Rasmussen, M, Gravel, S, Guillén, S, Nekhrizov, G, Leshtakov, K, Dimitrova, D, Theodossiev, N, Pettener, D, Luiselli, D, Sandoval, K, Moreno-Estrada, A, Li, Y, Wang, J, Gilbert, T, Willerslev, E, Greenleaf, W J & Bustamante, C D 2013, ' Pulling out the 1% : whole-genome capture for the targeted enrichment of ancient DNA sequencing libraries ', American Journal of Human Genetics, vol. 93, no. 5, pp. 852-864 . https://doi.org/10.1016/j.ajhg.2013.10.002
Accession number :
edsair.doi.dedup.....24f37d845f2cfe96274198bca225d7a7
Full Text :
https://doi.org/10.1016/j.ajhg.2013.10.002