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Pulling out the 1%:whole-genome capture for the targeted enrichment of ancient DNA sequencing libraries
- Source :
- Carpenter, M L, Buenrostro, J D, Valdiosera Morales, C, Schroeder, H, Allentoft, M E, Sikora, M, Rasmussen, M, Gravel, S, Guillén, S, Nekhrizov, G, Leshtakov, K, Dimitrova, D, Theodossiev, N, Pettener, D, Luiselli, D, Sandoval, K, Moreno-Estrada, A, Li, Y, Wang, J, Gilbert, T, Willerslev, E, Greenleaf, W J & Bustamante, C D 2013, ' Pulling out the 1% : whole-genome capture for the targeted enrichment of ancient DNA sequencing libraries ', American Journal of Human Genetics, vol. 93, no. 5, pp. 852-864 . https://doi.org/10.1016/j.ajhg.2013.10.002
- Publication Year :
- 2013
-
Abstract
- Most ancient specimens contain very low levels of endogenous DNA, precluding the shotgun sequencing of many interesting samples because of cost. Ancient DNA (aDNA) libraries often contain
- Subjects :
- Male
0106 biological sciences
Adolescent
Genomics
Computational biology
Biology
010603 evolutionary biology
01 natural sciences
Genome
Bone and Bones
Article
Deep sequencing
03 medical and health sciences
Principal Component Analysi
Neanderthal genome
MTDNA
Genetics
Humans
ANCIENT DNA
Genetics(clinical)
Genomic library
Environmental DNA
Child
History, Ancient
Genetics (clinical)
Gene Library
030304 developmental biology
Principal Component Analysis
0303 health sciences
Fossils
Shotgun sequencing
whole genome sequence
High-Throughput Nucleotide Sequencing
Nucleic Acid Hybridization
DNA
Mummies
Sequence Analysis, DNA
aDNA sequencing librarie
Ancient DNA
RNA
Human genome
Tooth
Hair
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Carpenter, M L, Buenrostro, J D, Valdiosera Morales, C, Schroeder, H, Allentoft, M E, Sikora, M, Rasmussen, M, Gravel, S, Guillén, S, Nekhrizov, G, Leshtakov, K, Dimitrova, D, Theodossiev, N, Pettener, D, Luiselli, D, Sandoval, K, Moreno-Estrada, A, Li, Y, Wang, J, Gilbert, T, Willerslev, E, Greenleaf, W J & Bustamante, C D 2013, ' Pulling out the 1% : whole-genome capture for the targeted enrichment of ancient DNA sequencing libraries ', American Journal of Human Genetics, vol. 93, no. 5, pp. 852-864 . https://doi.org/10.1016/j.ajhg.2013.10.002
- Accession number :
- edsair.doi.dedup.....24f37d845f2cfe96274198bca225d7a7
- Full Text :
- https://doi.org/10.1016/j.ajhg.2013.10.002