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Efficacy and safety of traditional Chinese medicine rehabilitation program in the treatment of knee osteoarthritis: a randomized controlled trial protocol
- Source :
- Annals of Palliative Medicine. 10:6909-6918
- Publication Year :
- 2021
- Publisher :
- AME Publishing Company, 2021.
-
Abstract
- Background Knee osteoarthritis (KOA) is a common joint disease worldwide, and the main cause of pain and disability in the elderly. Due to increased aging and rates of obesity of the global population, the number of patients with KOA is expected to increase. To reduce the burden of KOA, effective and safe interventions should be developed to reduce pain and improve range of motion, functionality, and quality of life. The aim of the proposed randomized controlled study was to evaluate the efficacy and safety of a traditional Chinese medicine (TCM) rehabilitation therapy in the treatment of KOA. Methods This multicenter, randomized, double-blind, parallel group, placebo-controlled trial will include a total of 200 patients with KOA. The enrolled patients will be randomly divided into the experimental group (n=100) and control group (n=100). The experimental group will receive basic treatment plus TCM rehabilitation therapy, while the control group will receive basic treatment plus physiotherapy regimen. Primary endpoints will include clinical efficacy outcomes, visual analog scale, Western Ontario and McMaster Universities Osteoarthritis Index score, and Knee Outcome Survey Activities of Daily Living Scale score. The data will help determine whether TCM rehabilitation therapy is beneficial for the treatment of KOA. Discussion The results will provide high-quality guidance for the current clinical treatment of KOA, and provide patients with more options for symptom relief. The findings from this study may provide updated evidence concerning the efficacy and safety of TCM for patients with KOA.
- Subjects :
- medicine.medical_specialty
Activities of daily living
Visual analogue scale
medicine.medical_treatment
Traditional Chinese medicine
Osteoarthritis
law.invention
Randomized controlled trial
Quality of life
law
Activities of Daily Living
medicine
Humans
Multicenter Studies as Topic
Medicine, Chinese Traditional
Aged
Pain Measurement
Randomized Controlled Trials as Topic
Advanced and Specialized Nursing
Rehabilitation
business.industry
Osteoarthritis, Knee
medicine.disease
Regimen
Treatment Outcome
Anesthesiology and Pain Medicine
Quality of Life
Physical therapy
business
Subjects
Details
- ISSN :
- 22245839 and 22245820
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- Annals of Palliative Medicine
- Accession number :
- edsair.doi.dedup.....24a124931abca0766f93b999d3ecd3e2