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7-Acetyl-8-(4-chlorophenyl)-3-ethylsulfanyl-6-hydroxy-1,6-dimethyl-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile
- Source :
- IUCrData, Vol 2, Iss 3, p x170390 (2017)
- Publication Year :
- 2017
- Publisher :
- International Union of Crystallography (IUCr), 2017.
-
Abstract
- In the title compound, C22H23ClN2O2S, the chlorophenyl ring is inclined to the pyridine ring of the isoquinoline ring system by 79.78 (4)°. The cyclohexane ring adopts a flattened boat conformation. In the crystal, dimers form through complementary sets of inversion-related O—H...O and C—H...O hydrogen bonds. These are connected into zigzag chains along the c-axis direction by pairwise C—H...N interactions that also form inversion dimers.
- Subjects :
- crystal structure
Nitrile
Stereochemistry
Cyclohexane conformation
010403 inorganic & nuclear chemistry
Ring (chemistry)
01 natural sciences
Medicinal chemistry
chemistry.chemical_compound
Sulfanyl
Pyridine
lcsh:QD901-999
Mathematics::Commutative Algebra
biology
010405 organic chemistry
Chemistry
Hydrogen bond
Quinoline
biology.organism_classification
isoquinolines
0104 chemical sciences
hydrogen bonds
Tetra
Condensed Matter::Strongly Correlated Electrons
lcsh:Crystallography
inversion dimers
Subjects
Details
- ISSN :
- 24143146
- Volume :
- 2
- Database :
- OpenAIRE
- Journal :
- IUCrData
- Accession number :
- edsair.doi.dedup.....23f4a6f2e4d7b31b785bd912e1dd91f4
- Full Text :
- https://doi.org/10.1107/s241431461700390x