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Current and emerging therapies for insomnia
- Source :
- The American journal of managed care. 26
- Publication Year :
- 2020
-
Abstract
- Up to 10% of the US adult population will experience chronic insomnia, with women and elderly individuals at particularly high risk. Cognitive behavioral therapy is the core treatment for insomnia. When cognitive behavioral therapy is not enough, medications can help patients overcome the barriers and learned behaviors that prevent a good night's sleep. Benzodiazepines and nonbenzodiazepine GABA-A receptor agonists are the traditional medications used to treat insomnia. More recently, orexin inhibitors have been introduced that may have fewer adverse effects, including the development of dependence. To date, only suvorexant and lemborexant have been approved for the treatment of insomnia. However, several other agents are in later stages of development. This article will review the available pharmacotherapeutic options for treating insomnia.
- Subjects :
- medicine.medical_specialty
medicine.medical_treatment
Nonbenzodiazepine
Adult population
Lemborexant
030226 pharmacology & pharmacy
03 medical and health sciences
Benzodiazepines
0302 clinical medicine
Sleep Initiation and Maintenance Disorders
mental disorders
medicine
Insomnia
Humans
Hypnotics and Sedatives
Intensive care medicine
Adverse effect
Aged
business.industry
Health Policy
Suvorexant
Cognitive behavioral therapy
Chronic insomnia
Female
medicine.symptom
business
Sleep
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 19362692
- Volume :
- 26
- Database :
- OpenAIRE
- Journal :
- The American journal of managed care
- Accession number :
- edsair.doi.dedup.....23bb44721cb5075e5b9371086e5dd20c