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Eosinophilic Lung Diseases: Diagnostic Accuracy of Thin-Section CT in 111 Patients
- Source :
- Radiology. 216:773-780
- Publication Year :
- 2000
- Publisher :
- Radiological Society of North America (RSNA), 2000.
-
Abstract
- To determine whether various eosinophilic lung diseases can be differentiated by means of thin-section computed tomography (CT).Thin-section CT scans in 111 patients with eosinophilic lung diseases-40 with chronic eosinophilic pneumonia, 16 with Churg-Strauss syndrome, 16 with allergic bronchopulmonary aspergillosis (ABPA), 13 with acute eosinophilic pneumonia, 12 with simple pulmonary eosinophilia, 11 with drug-induced eosinophilic pneumonia, and three with hypereosinophilic syndrome-were assessed independently by two observers. The observers recorded the abnormalities, diagnosis, and degree of confidence in the diagnosis.The two observers made a correct first-choice diagnosis on average in 61% of readings. The correct diagnosis was made in 78% of cases of chronic eosinophilic pneumonia; 81%, acute eosinophilic pneumonia; 44%, Churg-Strauss syndrome; 84%, ABPA; 17%, simple pulmonary eosinophilia; 27%, drug-induced eosinophilic pneumonia; and 33%, hypereosinophilic syndrome. The two observers made a correct diagnosis with a high degree of confidence in 36% of readings. There was moderate agreement between the observers for the correct diagnosis (kappa, 0.47) and for the correct diagnosis with a high degree of confidence (kappa, 0.59).Although eosinophilic lung diseases often can be differentiated by means of thin-section CT, correlation between CT findings and careful clinical evaluation are required for a definitive diagnosis.
- Subjects :
- Adult
Male
medicine.medical_specialty
Adolescent
government.form_of_government
Diagnostic accuracy
Sensitivity and Specificity
Diagnosis, Differential
hemic and lymphatic diseases
medicine
Eosinophilic pneumonia
Humans
Radiology, Nuclear Medicine and imaging
Thin section ct
Pulmonary Eosinophilia
Lung
Aged
business.industry
Respiratory disease
Middle Aged
respiratory system
Eosinophilic lung
Image Enhancement
medicine.disease
respiratory tract diseases
Acute eosinophilic pneumonia
government
Female
Radiology
Allergic bronchopulmonary aspergillosis
Tomography, X-Ray Computed
business
Subjects
Details
- ISSN :
- 15271315 and 00338419
- Volume :
- 216
- Database :
- OpenAIRE
- Journal :
- Radiology
- Accession number :
- edsair.doi.dedup.....23b86cc1871e9c04e0ffac34f75d371c