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Antimicrobial Properties, Cytotoxic Effects, and Fatty Acids Composition of Vegetable Oils from Purslane, Linseed, Luffa, and Pumpkin Seeds
- Source :
- Applied Sciences, Vol 11, Iss 5738, p 5738 (2021), Repositório Científico de Acesso Aberto de Portugal, Repositório Científico de Acesso Aberto de Portugal (RCAAP), instacron:RCAAP, Applied Sciences, Volume 11, Issue 12
- Publication Year :
- 2021
- Publisher :
- MDPI AG, 2021.
-
Abstract
- In the present study, the antimicrobial and cytotoxic activities, as well as the fatty acids composition in vegetable seed oils from linseed, purslane, luffa, and pumpkin were evaluated. For this purpose, two linseed oils and one luffa oil were commercially obtained, while purslane and pumpkin oils were obtained from own cultivated seeds. The results showed a variable fatty acids composition among the tested oils, with α-linolenic, linoleic, oleic, palmitic, and stearic acid being the most abundant compounds. In regards to particular oils, linseed oils were a rich source of α-linolenic acid, luffa and pumpkin oil were abundant in linoleic acid, while purslane oil presented a balanced composition with an almost similar amount of both fatty acids. Luffa oil was the most effective against two of the tested cancer cell lines, namely HeLa (cervical carcinoma) and NCI-H460 (non-small cell lung cancer), while it also showed moderate toxicity against non-tumor cells (PLP2 cell line). Regarding the antibacterial activity, linseed oil 3 and pumpkin oil showed the highest activity against most of the tested bacteria (especially against Enterobacter cloacae and Escherichia coli) with MIC and MBC values similar to the used positive controls (E211 and E224). All the tested oils showed significant antifungal activities, especially luffa and pumpkin oil, and for most of the tested fungi they were more effective than the positive controls, as for example in the case of Aspergillus versicolor, A. niger, and Penicillium verrucosum var. cyclopium. In conclusion, the results of our study showed promising antimicrobial and cytotoxic properties for the studied seed oils which could be partly attributed to their fatty acids composition, especially the long-chain ones with 12–18 carbons. This work was funded by the General Secretariat for Research and Technology of Greece and PRIMA foundation under the project PULPING (Prima2019-08). The authors are grateful to the Foundation for Science and Technology (FCT, Portugal) for financial support through national funds FCT/MCTES to CIMO (UIDB/00690/2020); for the financial support through national funding from the FCT, within the scope of the Project PRIMA Section 2—Multi-topic 2019: PulpIng (PRIMA/0007/2019); and L. Barros and Â. Fernandes thank the national funding by FCT, P.I., through the institutional scientific employment program-contract for their contracts. The authors are also grateful to the Ministry of Education, Science and Technological Development of the Republic of Serbia, grant number 451-03-9/2021-14/ 200007. info:eu-repo/semantics/publishedVersion
- Subjects :
- Omega-6 fatty acid
Technology
Portulaca oleracea L
Cytotoxicity
Linum usitatissimum L
Omega-3 fatty acid
Seed oils
01 natural sciences
Antibacterial properties
chemistry.chemical_compound
Linseed oil
General Materials Science
Food science
Antitumor activitie
Biology (General)
Instrumentation
Fluid Flow and Transfer Processes
omega-3 fatty acids
Physics
General Engineering
Luffa aegyptica Mill
04 agricultural and veterinary sciences
Antibacterial propertie
Antimicrobial
Engineering (General). Civil engineering (General)
040401 food science
Computer Science Applications
omega-6 fatty acids
Chemistry
cytotoxicity
Composition (visual arts)
Stearic acid
TA1-2040
Antifungal properties
seed oils
food.ingredient
QH301-705.5
Linoleic acid
QC1-999
Antitumor activities
0404 agricultural biotechnology
food
Omega-3 fatty acids
Penicillium verrucosum
Omega-6 fatty acids
antibacterial properties
QD1-999
Antifungal propertie
Pumpkin seed
010405 organic chemistry
Process Chemistry and Technology
Cucurbita maxima L
food.food
0104 chemical sciences
chemistry
antifungal properties
Aspergillus versicolor
Subjects
Details
- Language :
- English
- ISSN :
- 20763417
- Volume :
- 11
- Issue :
- 5738
- Database :
- OpenAIRE
- Journal :
- Applied Sciences
- Accession number :
- edsair.doi.dedup.....239b8e9827f1732bcbd2b2416351df0e