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Expansion of large granular lymphocytes following Pseudomonas infection in a patient with adult-onset Still's disease
- Source :
- Modern Rheumatology. 16:101-104
- Publication Year :
- 2006
- Publisher :
- Oxford University Press (OUP), 2006.
-
Abstract
- We report a patient who had a 4-year history of adult-onset Still's disease (AOSD) and showed a prominent increase in large granular lymphocytes (LGL) when she developed severe Pseudomonas conjunctivitis due to Pseudomonas aeruginosa, skin eruptions, liver damage, and abnormal findings in coagulation studies, without any evidence of active viral activation, hemophagocytosis, or malignancies. The increased LGL cells were CD3(+)CD8(+), and disappeared promptly after the administration of antibiotics combined with prednisolone, with subsequent stabilization of her general condition.
- Subjects :
- Adult
medicine.medical_specialty
CD3 Complex
medicine.drug_class
CD8 Antigens
Prednisolone
T-Lymphocytes
CD3
Antibiotics
medicine.disease_cause
Rheumatology
Pseudomonas infection
Internal medicine
medicine
Humans
Pseudomonas Infections
biology
Pseudomonas aeruginosa
business.industry
Meropenem
Decompression, Surgical
medicine.disease
Combined Modality Therapy
Anti-Bacterial Agents
Treatment Outcome
Immunology
biology.protein
Drug Therapy, Combination
Female
Thienamycins
Hemophagocytosis
business
Still's Disease, Adult-Onset
CD8
medicine.drug
Subjects
Details
- ISSN :
- 14397609 and 14397595
- Volume :
- 16
- Database :
- OpenAIRE
- Journal :
- Modern Rheumatology
- Accession number :
- edsair.doi.dedup.....23693ca477f53e9d9c02398b7a9fe0e8