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Competitive endogenous RNA in colorectal cancer: A systematic review
- Source :
- Gene. 645
- Publication Year :
- 2017
-
Abstract
- Colorectal cancer is one of the most common malignant tumours. Competitive endogenous RNA (ceRNA) networks have been hypothesized, in which various RNAs regulate each other's expression using microRNA response elements (MREs). Recent evidence has highlighted the crucial regulatory roles of ceRNA networks in colorectal cancer. In this review, we summarize the present research methods as well as the currently known ceRNA competitors and targets in colorectal cancer. In addition, we discuss the significance of ceRNA and shortcomings of current studies of colorectal cancer.
- Subjects :
- 0301 basic medicine
Colorectal cancer
Endogeny
Biology
Response Elements
03 medical and health sciences
0302 clinical medicine
microRNA
Genetics
medicine
Humans
Gene Regulatory Networks
Competing endogenous RNA
RNA
General Medicine
RNA, Circular
medicine.disease
Gene Expression Regulation, Neoplastic
MicroRNAs
030104 developmental biology
030220 oncology & carcinogenesis
Cancer research
RNA, Long Noncoding
Colorectal Neoplasms
Pseudogenes
Subjects
Details
- ISSN :
- 18790038
- Volume :
- 645
- Database :
- OpenAIRE
- Journal :
- Gene
- Accession number :
- edsair.doi.dedup.....23540a16247a9478e28444fb630ffde0