New Multidrug Resistance Reversal Agents

Authors :: Masami Kawase
Noboru Motohashi
Source :: Current Drug Targets. 4:31-43
Publication Year :: 2003
Publisher :: Bentham Science Publishers Ltd., 2003.
Abstract: Multidrug resistance (MDR) to antitumor agents represents a significant challenge to effective chemotherapy. The use of MDR modulators is a promising approach to overcome the undesired MDR phenotype. The more effective MDR modulators are urgently needed for clinical use. This review focuses on literatures published in 1998-2001.