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Two-year follow-up of 196 interstitial lung disease patients after ICU stay
- Source :
- The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. 25(3)
- Publication Year :
- 2021
-
Abstract
- OBJECTIVE: Interstitial lung diseases (ILDs) are associated with poor prognosis in the intensive care unit (ICU). We aimed to assess factors associated with hospital mortality in ILD patients admitted to the ICU and to investigate long-term outcome.MATERIAL AND METHODS: This was a retrospective study in a teaching hospital specialised in ILD management. Patients with ILD who were hospitalised in the ICU between 2000 and 2014 were included. Independent predictors of hospital mortality were identified using logistic regression.RESULTS: A total of 196 ILD patients were admitted to the ICU during the study period. Overall hospital mortality was 55%. Two years after ICU admission, 70 (36%) patients were still alive. Of the 196 patients, 108 (55%) required invasive mechanical ventilation, of whom 21 (20%) were discharged alive from hospital. Acute exacerbation of ILD and multi-organ failure were highly associated with hospital mortality (OR 5.4, 95% CI 1.9–15.5 and OR 12.6, 95% CI 4.9–32.5, respectively).CONCLUSION: Hospital mortality among ILD patients hospitalised in the ICU was high, but even where invasive mechanical ventilation was required, a substantial number of patients were discharged alive from hospital. Multi-organ failure could lead to major ethical concerns.
- Subjects :
- Pulmonary and Respiratory Medicine
medicine.medical_specialty
Exacerbation
medicine.medical_treatment
Discharged alive
behavioral disciplines and activities
law.invention
law
medicine
Humans
Icu stay
Hospital Mortality
Retrospective Studies
Mechanical ventilation
Lung
business.industry
Interstitial lung disease
Retrospective cohort study
Length of Stay
medicine.disease
Prognosis
Intensive care unit
Respiration, Artificial
Intensive Care Units
Infectious Diseases
medicine.anatomical_structure
Emergency medicine
business
Lung Diseases, Interstitial
Follow-Up Studies
Subjects
Details
- ISSN :
- 18157920
- Volume :
- 25
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
- Accession number :
- edsair.doi.dedup.....22c952d8c06c01db550014635706138a