Back to Search
Start Over
NACP-REP1 polymorphism is not involved in Parkinson's disease: a case-control study in a population sample from southern Italy
- Source :
- Neuroscience letters, 351 (2003): 75–78., info:cnr-pdr/source/autori:Spadafora P,1; Annesi G,1; Pasqua AA,1; Serra P,1; Ciro Candiano IC,1; Carrideo S,1; Tarantino P,1; Civitelli D,1; De Marco EV,1; Nicoletti G,1; Annesi F,1; Quattrone A.1-2/titolo:NACP-REP1 polymorphism is not involved in Parkinson's disease: a case-control study in a population sample from southern Italy./doi:/rivista:Neuroscience letters (Print)/anno:2003/pagina_da:75/pagina_a:78/intervallo_pagine:75–78/volume:351
- Publication Year :
- 2003
-
Abstract
- Contradictory evidence has been reported on the role of the polymorphic mixed dinucleotide repeat (NACP-REP1) of the α-synuclein gene as a risk factor for sporadic Parkinson's disease (PD). In the present study we genotyped the NACP-REP1 polymorphism in 189 PD patients from southern Italy and 182 healthy control subjects. We failed to demonstrate an association of any NACP-REP1 allele with PD.
- Subjects :
- Oncology
Male
medicine.medical_specialty
Pathology
Parkinson's disease
Genotype
Synucleins
Nerve Tissue Proteins
Disease
Degenerative disease
Gene Frequency
Polymorphism (computer science)
Internal medicine
medicine
Humans
Genetic Predisposition to Disease
Genetic Testing
Allele
Risk factor
Dinucleotide Repeats
Aged
Aged, 80 and over
Polymorphism, Genetic
business.industry
General Neuroscience
Case-control study
Parkinson Disease
Middle Aged
medicine.disease
Italy
Case-Control Studies
Synuclein
alpha-Synuclein
Female
business
Subjects
Details
- ISSN :
- 03043940
- Volume :
- 351
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Neuroscience letters
- Accession number :
- edsair.doi.dedup.....22c813709027db43714f32bf31cc8f7f