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Supplementary Materials, Figures 1 - 3, Tables 1 - 4, 6 - 8 from The 19q12 Bladder Cancer GWAS Signal: Association with Cyclin E Function and Aggressive Disease

Authors :
Ludmila Prokunina-Olsson
Nathaniel Rothman
Debra T. Silverman
Stephen M. Hewitt
Stephen J. Chanock
Joseph Fraumeni
William Wheeler
Laurie Burdette
Amy Hutchinson
Charles C. Chung
Xiang Deng
Zhaoming Wang
H. Barton Grossman
Giuseppe Mastrangelo
Cecilia Arici
Sofia Pavanello
Angela Carta
Stefano Porru
Eva Comperat
Morgan Roupret
Geraldine Cancel-Tassin
Olivier Cussenot
Christopher A. Haiman
Jian-Min Yuan
David Van Den Berg
Malcolm C. Pike
Mariana C. Stern
Manuela Gago-Dominguez
David V. Conti
Victoria K. Cortessis
Rebecca J. Rodabough
Chancellor Hohensee
Charles Kooperberg
Jarmo Virtamo
Stephanie J. Weinstein
Demetrius Albanes
W. Ryan Diver
Eric J. Jacobs
Susan M. Gapstur
Sara Lindstrom
Peter Kraft
David Hunter
Edward Govannucci
Immaculata De Vivo
Constance Chen
Jennifer Prescott
Elio Riboli
Jenny Chang-Claude
Paul Brennan
Anne Tjønneland
Ruth C. Travis
Miren Dorronsoro
Vittorio Krogh
Elisabete Weiderpass
Gianluca Severi
Börje Ljungberg
Dimitrios Trichopoulos
H. Bas Bueno-de-Mesquita
Afshan Siddiq
Paolo Vineis
Neil E. Caporaso
Maria T. Landi
Amanda Black
Robert L. Grubb
Gerald L. Andriole
Mark Purdue
Xifeng Wu
Josep Lloreta
Reina Garcia-Closas
Alfredo Carrato
Consol Serra
Adonina Tardon
Manolis Kogevinas
Nuria Malats
GM Monawar Hosain
Masatoshi Kida
Michael A. Jones
Liliana Guedez
Alan Schned
Adam Mumy
Alison Johnson
McAnthony Tarway
Margaret R. Karagas
Andrea B. Apolo
Molly Schwenn
Kris Ylaya
Ashley Paquin
Dalsu Baris
Brian Muchmore
Montserrat Garcia-Closas
Alexandra Scott-Johnson
Nilanjan Chatterjee
Patricia Porter-Gill
Wei Tang
Jonine D. Figueroa
Petra Lenz
Lee E. Moore
Indu Kohaar
Yi-Ping Fu
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Supplementary Figure 1: Electrophoretic mobility shift assays (EMSA) for CCNE1 SNPs rs8102137 and rs7257330. Supplementary Figure 2: Alignment of cyclin E protein isoforms - WT1, WT2 and ES and ET. Supplementary Figure 3: Functional analysis of cyclin E isoforms.Supplementary Table 1: Description of sub-studies included in NCI-GWAS1 and GWAS2 of bladder cancer. Supplementary Table 2: Characteristics of bladder tissue samples used for mRNA expression analysis. Supplementary Table 3: PCR primers, genotyping and gene expression assays, EMSA probes and antibodies. Supplementary Table 4: Bladder cancer stage and grade information for patients in the combined GWAS1+2 set. Supplementary Table 6: Association with bladder cancer risk with mutual adjustment for CCNE1 variants. Supplementary Table 7: Association with bladder cancer risk for CCNE1 variants previously associated with other cancers and for two non-synonymous coding variants. Supplementary Table 8: Association between cyclin E protein expression (IHC scores), bladder cancer patient characteristics and CCNE1 variants.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....22ba7cb94effb1a6b98d66cf6eaf8513