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Assessment of dioxin and dioxin-like compounds in mainstream smoke from selected US cigarette brands and reference cigarettes
Assessment of dioxin and dioxin-like compounds in mainstream smoke from selected US cigarette brands and reference cigarettes
- Source :
- Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 46(5)
- Publication Year :
- 2007
-
Abstract
- Mainstream cigarette smoke (MSS) from 12 US cigarette brands and two reference cigarettes was evaluated to determine concentrations of dioxins (i.e., polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and dioxin-like polychlorinated biphenyls (PCBs)). The study included three 'tar' ranges based on Federal Trade Commission (FTC) determination: Low Yield (LY)or = 5.5, Medium Yield (MY) 9.6-12.2, and High Yield (HY)or = 14.5 mg/cig. Of the brands studied, the HY cigarettes yielded the greatest mean concentrations of 2005 World Health Organization Toxic Equivalents (WHO-TEQs) on a per cigarette basis. WHO-TEQ levels in LY cigarettes were significantly lower than for HY cigarettes (p=0.039) on a yield per cigarette basis and WHO-TEQ concentrations correlated with 'tar' yield (r=0.73, p=0.007), as did concentration on a WHO-TEQ per body mass per day basis (r=0.73, p=0.007). However, a statistically significant relationship was not observed between 'tar' yield levels and WHO-TEQ concentrations on a per mg Total Particulate Matter (TPM) basis. Concentrations for all brands tested ranged from 0.44 to 3.88 fg WHO-TEQ/mg TPM. Maximum daily exposure estimates calculated from this range (0.004-0.074 pg WHO-TEQ/kg bw/day) are below the current WHO Tolerable Daily Intake range of 1-5 pg/kg bw/day.
- Subjects :
- Tolerable daily intake
Polychlorinated Dibenzodioxins
Polychlorinated dibenzodioxins
Toxicology
Dioxins
Risk Assessment
World health
chemistry.chemical_compound
Tar (tobacco residue)
Animal science
Smoke
Tobacco
Sidestream smoke
Daily exposure
Chemistry
General Medicine
Reference Standards
Polychlorinated Biphenyls
United States
Data Interpretation, Statistical
Environmental Pollutants
Particulate Matter
Polychlorinated dibenzofurans
Filtration
Food Science
Subjects
Details
- ISSN :
- 02786915
- Volume :
- 46
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
- Accession number :
- edsair.doi.dedup.....22b544cb37bcfd64c1de21a11e96698f