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Neural basis of self-initiative in relation to apathy in a student sample
- Source :
- Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017), Scientific Reports, 7:3264. Nature Publishing Group, Scientific Reports
- Publication Year :
- 2017
- Publisher :
- Nature Publishing Group, 2017.
-
Abstract
- Human behaviour can be externally driven, e.g. catching a falling glass, or self-initiated and goal-directed, e.g. drinking a cup of coffee when one deems it is time for a break. Apathy refers to a reduction of self-initiated goal-directed or motivated behaviour, frequently present in neurological and psychiatric disorders. The amount of undertaken goal-directed behaviour varies considerably in clinical as well as healthy populations. In the present study, we investigated behavioural and neural correlates of self-initiated action in a student sample (N = 39) with minimal to high levels of apathy. We replicated activation of fronto-parieto-striatal regions during self-initiation. The neural correlates of self-initiated action did not explain varying levels of apathy in our sample, neither when mass-univariate analysis was used, nor when multivariate patterns of brain activation were considered. Other hypotheses, e.g. regarding a putative role of deficits in reward anticipation, effort expenditure or executive difficulties, deserve investigation in future studies.
- Subjects :
- Adult
Male
Neural basis of self
medicine.medical_specialty
REWARD
Science
Apathy
Models, Neurological
Neuroimaging
Intention
PREFRONTAL CORTEX
Brain mapping
Article
Developmental psychology
Young Adult
03 medical and health sciences
0302 clinical medicine
BASAL GANGLIA
PARKINSONS-DISEASE
SCHIZOPHRENIA
Image Processing, Computer-Assisted
medicine
Humans
Psychiatry
SUBCLINICAL NEGATIVE SYMPTOMS
SCALE
Brain Mapping
Motivation
Neural correlates of consciousness
Multidisciplinary
Brain
medicine.disease
DEPRESSION
Magnetic Resonance Imaging
Anticipation
030227 psychiatry
ORBITOFRONTAL CORTEX
Action (philosophy)
Schizophrenia
Medicine
EXPERIENCE
Female
Orbitofrontal cortex
medicine.symptom
Psychology
030217 neurology & neurosurgery
Subjects
Details
- Language :
- English
- ISSN :
- 20452322
- Volume :
- 7
- Database :
- OpenAIRE
- Journal :
- Scientific Reports
- Accession number :
- edsair.doi.dedup.....22af6c3527cf06639f703f9416088ea2