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Cardioprotective Effect of Resveratrol and Resveratroloside

Authors :
Nina I. Komarova
Tatiana V. Latysheva
Artem D. Rogachev
Tolstikov Genrikh A
Sergey E. Naumenko
Michael A. Gilinsky
Nariman F. Salakhutdinov
Source :
Cardiovascular & Hematological Agents in Medicinal Chemistry. 11:207-210
Publication Year :
2014
Publisher :
Bentham Science Publishers Ltd., 2014.

Abstract

Cardioprotective effect of resveratrol and resveratroloside was determined in ischemia-reperfusion experiments on rats. It was found that single intraperitoneal administration of any compound (10 mg/kg) followed by 30-min ischemia and 120-min reperfusion resulted in statistically significant decrease of myocardial infarct area (55.0±4.0% for control group; 40.7±4.4% for the group 1 received resveratrol; 41.6±4.8% for the group 2 received resveratroloside). The cardioprotective effect of resveratroloside was detected for the first time.

Details

ISSN :
18715257
Volume :
11
Database :
OpenAIRE
Journal :
Cardiovascular & Hematological Agents in Medicinal Chemistry
Accession number :
edsair.doi.dedup.....22a6046a8795c1c846ac6ef2589b3309