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Multicentre Italian study of SARS-CoV-2 infection in children and adolescents, preliminary data as at 10 April 2020

Authors :
Garazzino, S.
Montagnani, C.
Dona, D.
Meini, A.
Felici, E.
Vergine, G.
Bernardi, S.
Giacchero, R.
Vecchio, A. L.
Marchisio, P.
Nicolini, G.
Pierantoni, L.
Rabbone, I.
Banderali, G.
Denina, M.
Venturini, E.
Krzysztofiak, A.
Badolato, R.
Bianchini, S.
Galli, L.
Villani, A.
Castelli-Gattinara, G.
Salvini, F.
Abbagnato, L.
Castagnola, E.
Dodi, I.
Ghitti, C.
Lippi, P.
Agostiniani, R.
Cherubini, S.
Valentini, P.
Gianino, P.
Vaccaro, A.
Manzoni, P.
Verna, P.
Comberiati, P.
Di Filippo, P.
Gallia, P.
Battezzati, G.
Fiore, L.
Dalmazzo, C.
Tappi, E.
Lazzerini, M.
Tovo, P. -A.
Scolfaro, C.
Pruccoli, G.
Ramenghi, U.
Giaquinto, C.
da Dalt, L.
Tornese, G.
Berlese, P.
Plebani, A.
Manno, E. C.
Santilli, V.
Lancella, L.
Cursi, L.
Campana, A.
Bozzola, E.
Bosis, S.
Lanari, M.
Pecoraro, C.
Del Barba, P.
Nicastro, E.
Esposito, S.
Zuccotti, G. V.
Corsello, G.
Cardinale, F.
Tocco, A. M.
Ballardini, G.
Agostoni, C.
Chiappini, E.
Indolfi, G.
Anna, B.
Cazzato, S.
Zavarise, G.
Pignata, C.
Marchetti, F.
Garazzino S.
Montagnani C.
Dona D.
Meini A.
Felici E.
Vergine G.
Bernardi S.
Giacchero R.
Vecchio A.L.
Marchisio P.
Nicolini G.
Pierantoni L.
Rabbone I.
Banderali G.
Denina M.
Venturini E.
Krzysztofiak A.
Badolato R.
Bianchini S.
Galli L.
Villani A.
Castelli-Gattinara G.
Salvini F.
Abbagnato L.
Castagnola E.
Dodi I.
Ghitti C.
Lippi P.
Agostiniani R.
Cherubini S.
Valentini P.
Gianino P.
Vaccaro A.
Manzoni P.
Verna P.
Comberiati P.
Di Filippo P.
Gallia P.
Battezzati G.
Fiore L.
Dalmazzo C.
Tappi E.
Lazzerini M.
Tovo P.-A.
Scolfaro C.
Pruccoli G.
Ramenghi U.
Giaquinto C.
da Dalt L.
Tornese G.
Berlese P.
Plebani A.
Manno E.C.
Santilli V.
Lancella L.
Cursi L.
Campana A.
Bozzola E.
Bosis S.
Lanari M.
Pecoraro C.
Del Barba P.
Nicastro E.
Esposito S.
Zuccotti G.V.
Corsello G.
Cardinale F.
Tocco A.M.
Ballardini G.
Agostoni C.
Chiappini E.
Indolfi G.
Anna B.
Cazzato S.
Zavarise G.
Pignata C.
Marchetti F.
Garazzino, S.
Montagnani, C.
Dona, D.
Meini, A.
Felici, E.
Vergine, G.
Bernardi, S.
Giacchero, R.
Vecchio, A. L.
Marchisio, P.
Nicolini, G.
Pierantoni, L.
Rabbone, I.
Banderali, G.
Denina, M.
Venturini, E.
Krzysztofiak, A.
Badolato, R.
Bianchini, S.
Galli, L.
Villani, A.
Castelli-Gattinara, G
Tornese, G
Filippo Salvini, Laura Abbagnato, Elio Castagnola, Icilio Dodi, Cesare Ghitti, Paola Lippi, Rino Agostiniani, Simonetta Cherubini, Piero Valentini, Paola Gianino, Angelina Vaccaro, Paolo Manzoni, Paola Verna, Pasquale Comberiati, Paola Di Filippo, Paola Gallia, Gianna Battezzati, Ludovica Fiore, Cristina Dalmazzo, Eleonora Tappi, Marta Lazzerini, PierAngelo Tovo, Carlo Scolfaro, Giulia Pruccoli, Ugo Ramenghi, Carlo Giaquinto, Liviana Da Dalt, Gianluca Tornese, Paola Berlese, Alessandro Plebani, Emma Concetta Manno, Veronica Santilli, Laura Lancella, Laura Cursi, Andrea Campana, Elena Bozzola, Samantha Bosis, Marcello Lanari, Carmine Pecoraro, Paolo Del Barba, Emanuele Nicastro, Silvia Garazzino, Carlotta Montagnani, Daniele Donà, Antonella Meini, Enrico Felici, Gianluca Vergine, Stefania Bernardi, Roberta Giacchero, Andrea Lo Vecchio, Paola Marchisio, Giangiacomo Nicolini, Luca Pierantoni, Ivana Rabbone, Giuseppe Banderali, Marco Denina, Elisabetta Venturini, Andrzej Krzysztofiak , Raffaele Badolato, Sonia Bianchini, Luisa Galli, Alberto Villani , Guido Castelli-Gattinara, Susanna Esposito, Gian Vincenzo Zuccotti, Giovanni Corsello, Fabio Cardinale, Anna Maria Tocco, Giuseppina Ballardini, Carlo Agostoni, Elena Chiappini, Giuseppe Indolfi, Bussolini Anna, Salvatore Cazzato, Giorgio Zavarise, Claudio Pignata, Federico Marchetti
Lo Vecchio, A.
Castelli-Gattinara, G.
Source :
Eurosurveillance
Publication Year :
2020

Abstract

Data on features of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in children and adolescents are scarce. We report preliminary results of an Italian multicentre study comprising 168 laboratory-confirmed paediatric cases (median: 2.3 years, range: 1 day–17.7 years, 55.9% males), of which 67.9% were hospitalised and 19.6% had comorbidities. Fever was the most common symptom, gastrointestinal manifestations were frequent; two children required intensive care, five had seizures, 49 received experimental treatments and all recovered.

Subjects

Subjects :
Male
Pediatrics
Epidemiology
Protease Inhibitor
Comorbidity
medicine.disease_cause
Clinical Laboratory Technique
Severe Acute Respiratory Syndrome
Disease Outbreaks
Feces
0302 clinical medicine
Settore MED/38 - Pediatria Generale E Specialistica
COVID-19 Testing
Retrospective Studie
Pandemic
030212 general & internal medicine
Viral
Child
Coronavirus
Pediatric
Disease Outbreak
Coinfection
Hospitals, Pediatric
Settore MED/38
Hospitals
Diarrhea
Treatment Outcome
SARS-CoV-2 infection
children
covid-19
hydroxychloroquine
pneumonia
Adolescent
Antiviral Agents
Betacoronavirus
COVID-19
Child, Preschool
Chronic Disease
Clinical Laboratory Techniques
Coronavirus Infections
Female
Fever
Humans
Immunocompromised Host
Infant
Infant, Newborn
Italy
Noninvasive Ventilation
Pandemics
Pneumonia, Viral
Protease Inhibitors
Retrospective Studies
SARS-CoV-2
medicine.symptom
Rapid Communication
Human
medicine.medical_specialty
Coronaviru
03 medical and health sciences
030225 pediatrics
Virology
Intensive care
medicine
Preschool
Antiviral Agent
Betacoronaviru
business.industry
Coronavirus Infection
Public Health, Environmental and Occupational Health
Retrospective cohort study
medicine.disease
Newborn
Pneumonia
Fece
business

Details

Language :
English
Database :
OpenAIRE
Journal :
Eurosurveillance
Accession number :
edsair.doi.dedup.....2274ac45f53691c1d45add80c1eed1fd

Tools

Authors Abstract Subjects Details