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Prevalence of strongyloidiasis and schistosomiasis among migrants: a systematic review and meta-analysis
- Source :
- The Lancet Global Health. 7:e236-e248
- Publication Year :
- 2019
- Publisher :
- Elsevier BV, 2019.
-
Abstract
- Summary Background Global migration from regions where strongyloidiasis and schistosomiasis are endemic to non-endemic countries has increased the potential individual and public health effect of these parasitic diseases. We aimed to estimate the prevalence of these infections among migrants to establish which groups are at highest risk and who could benefit from screening. Methods We did a systematic review and meta-analysis of strongyloidiasis and schistosomiasis prevalence among migrants born in endemic countries. Original studies that included data for the prevalence of Strongyloides or Schistosoma antibodies in serum or the prevalence of larvae or eggs in stool or urine samples among migrants originating from countries endemic for these parasites and arriving or living in host countries with low endemicity—specifically the USA, Canada, Australia, New Zealand, Israel, and 23 western European countries—were eligible for inclusion. Pooled estimates of the prevalence of strongyloidiasis and schistosomiasis by stool or urine microscopy for larvae or eggs or serum antibodies were calculated with a random-effects model. Heterogeneity was explored by stratification by age, region of origin, migrant class, period of study, and type of serological antigen used. Findings 88 studies were included. Pooled strongyloidiasis seroprevalence was 12·2% (95% CI 9·0–15·9%; I2 96%) and stool-based prevalence was 1·8% (1·2–2·6%; 98%). Migrants from east Asia and the Pacific (17·3% [95% CI 4·1–37·0]), sub-Saharan Africa (14·6% [7·1–24·2]), and Latin America and the Caribbean (11·4% [7·8–15·7]) had the highest seroprevalence. Pooled schistosomiasis seroprevalence was 18·4% (95% CI 13·1–24·5; I2 97%) and stool-based prevalence was 0·9% (0·2–1·9; 99%). Sub-Saharan African migrants had the highest seroprevalence (24·1·% [95% CI 16·4–32·7]). Interpretation Strongyloidiasis affects migrants from all global regions, whereas schistosomiasis is focused in specific regions and most common among sub-Saharan African migrants. Serological prevalence estimates were several times higher than stool estimates for both parasites. These data can be used to inform screening decisions for migrants and support the use of serological screening, which is more sensitive and easier than stool testing. Funding None.
- Subjects :
- Canada
Endemic Diseases
Far East
030231 tropical medicine
Prevalence
Emigrants and Immigrants
Schistosomiasis
Pacific Islands
Feces
03 medical and health sciences
0302 clinical medicine
Blood serum
Seroepidemiologic Studies
Africa South of the Sahara
Humans
Mass Screening
Medicine
Seroprevalence
Serologic Tests
030212 general & internal medicine
Israel
Mass screening
Schistosoma
biology
Asia, Eastern
business.industry
Australia
General Medicine
medicine.disease
biology.organism_classification
United States
Europe
Latin America
Strongyloidiasis
Caribbean Region
Strongyloides
business
New Zealand
Demography
Subjects
Details
- ISSN :
- 2214109X
- Volume :
- 7
- Database :
- OpenAIRE
- Journal :
- The Lancet Global Health
- Accession number :
- edsair.doi.dedup.....223da6637bb9228360819cb97fb77f2f