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Histochemical characterization of mucosubstances in synovial sarcoma
- Source :
- The American journal of surgical pathology. 8(6)
- Publication Year :
- 1984
-
Abstract
- Six cases of synovial sarcoma were examined histochemically in order to clarify the components of mucosubstances in the tumor tissues. The tumors were classified into 1) monophasic type, 2) predominantly monophasic type with focal biphasic differentiation, and 3) biphasic type. The former two groups and sarcomatous areas in the biphasic tumors contained various amounts of hyaluronic acid, chondroitin sulfate, and, in some cases, heparitin sulfate. By contrast, the epithelioid regions in the biphasic-type tumors had periodic acid-Schiff-positive glycoproteins which contained various amounts of sialic acid, in addition to hyaluronic acid and chondroitin sulfate. The significance of the presence of glycoproteins in the mesenchymal tumors is emphasized. It seems likely that the synovial sarcomas contain various kinds of mucosubstances and that sensitivity to hyaluronidase treatment is not necessarily the diagnostic criterion of synovial sarcoma.
- Subjects :
- Adult
Male
Pathology
medicine.medical_specialty
Pathology and Forensic Medicine
chemistry.chemical_compound
Hyaluronidase
Hyaluronic acid
medicine
Humans
Chondroitin sulfate
Hyaluronic Acid
Glycoproteins
chemistry.chemical_classification
Mucous Membrane
Staining and Labeling
Histocytochemistry
Mesenchymal stem cell
Chondroitin Sulfates
Synovial Membrane
Sarcoma
Middle Aged
medicine.disease
Synovial sarcoma
N-Acetylneuraminic Acid
Sialic acid
chemistry
Sialic Acids
Immunohistochemistry
Surgery
Female
Heparitin Sulfate
Anatomy
Glycoprotein
medicine.drug
Subjects
Details
- ISSN :
- 01475185
- Volume :
- 8
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- The American journal of surgical pathology
- Accession number :
- edsair.doi.dedup.....223553babf3c264a777499400766316b