Back to Search
Start Over
Screening-confirmation strategy for nanomaterials involving spectroscopic analytical techniques and its application to the control of silver nanoparticles in pastry samples
- Source :
- Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 246:119015
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- The full characterization of nanomaterials (NMs), which requires a range of different and expensive equipment, is not always necessary to meet certain demands of information. Qualitative analytical methods are ideal alternatives when only a piece of information is required. In this work, a qualitative method for the screening of NMs has been developed and statistically validated for the first time, with silver nanoparticles (AgNPs) as a proof of concept. It is based on the generation of chemiluminescence of the luminol/Ag+ system in alkaline media in the presence of AgNPs. Measurements are obtained in a short time with a simple instrument. Probability of detection (POD) curves were constructed at three cut-off values next to the limit of detection of the chemiluminescent method. The unreliability region (UR) was from 0.50 to 1.82 μg L−1. Currently, no regulation on AgNPs exists, but the present method was successfully tested for a hypothetical threshold of 2.5 μg L−1 of 40 nm AgNPs. The method was applied to silver colored pearls, with silver (E-174) or aluminum (E-173) coating, used for decoration of pastry. Performance parameters such as false negative and positive rates as well as specificity, sensitivity and reliability rates were calculated for validation. The results of the screening method were confirmed by asymmetric flow field flow fractionation coupled to inductively coupled plasma mass spectrometry (AF4-ICP-MS). The proposed screening method is simple, fast, economic, and easy to transfer to routine laboratories in the field of food safety.
- Subjects :
- Silver
Metal Nanoparticles
Nanotechnology
02 engineering and technology
010402 general chemistry
01 natural sciences
Mass Spectrometry
Silver nanoparticle
Analytical Chemistry
Nanomaterials
law.invention
Luminol
chemistry.chemical_compound
law
Particle Size
Instrumentation
Inductively coupled plasma mass spectrometry
Spectroscopy
Reliability (statistics)
Chemiluminescence
Detection limit
Chemistry
Reproducibility of Results
021001 nanoscience & nanotechnology
Atomic and Molecular Physics, and Optics
0104 chemical sciences
Asymmetric flow field flow fractionation
0210 nano-technology
Subjects
Details
- ISSN :
- 13861425
- Volume :
- 246
- Database :
- OpenAIRE
- Journal :
- Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
- Accession number :
- edsair.doi.dedup.....22319cb0c622c4c2bd04815ab9c7b1f3