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Pelvic lymph node dissection for cervical or bladder cancer

Authors :
Jasmijn Vaneman
Heleen J. van Beekhuizen
Joost L. Boormans
Patricia C. Ewing-Graham
Geert J. L. H. van Leenders
Ramon G. V. Smolders
H C. van Doorn
Gynecological Oncology
Urology
Pathology
Source :
Virchows Archiv. Springer-Verlag
Publication Year :
2023

Abstract

Diagnosis of lymph node metastases in pelvic lymph node dissection (PLND) is important for staging and treatment. Standard practice is to submit visible or palpable lymph nodes for histology. We assessed the added value of embedding all residual fatty tissue.Patients (n = 85) who underwent PLND for cervical (n = 50) or bladder cancer (n = 35) between 2017 and 2019 were included. Study approval was obtained (MEC-2022-0156, 18.03.2022, retrospectively registered).The median lymph node yield with conventional pathological dissection was 21 nodes (Interquartile range (IQR) 18–28). This led to discovery of positive lymph nodes in 17 (20%) patients. Extended pathological assessment found 7 (IQR 3-12) additional nodes, but did not result in identification of more node metastases.Histopathological analysis of residual fatty tissue harvested at PLND resulted in an increased lymph node yield, but not in the detection of additional lymph node metastases.

Details

Language :
English
ISSN :
09456317
Database :
OpenAIRE
Journal :
Virchows Archiv
Accession number :
edsair.doi.dedup.....222743aedc3925dc8267af97b3190642