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Lung cancer: intermittent irradiation synchronized with respiratory motion--results of a pilot study
- Source :
- Radiology. 207:779-783
- Publication Year :
- 1998
- Publisher :
- Radiological Society of North America (RSNA), 1998.
-
Abstract
- To test the feasibility of a system for intermittent irradiation synchronized with respiratory motion in a clinical setting.A newly developed gate pulse controller that starts and stops irradiation at a chosen phase of the respiratory cycle by controlling a linear accelerator was used in six patients with lung cancer. A laser displacement sensor was used for the detection of respiratory motion. Three patients underwent radiation therapy during the cycles between 50% expiration and 50% inspiration (step 1), and three patients underwent radiation therapy during the cycles between 70% expiration and 30% inspiration (step 2).The system functioned well; irradiation was verified with portal verification radiography in all six patients. The range of the tumor position during synchronized irradiation was detectable with fast portal localization radiography. The treatment times for steps 1 and 2 were 1.38-1.71 and 2.03-2.18 times longer, respectively, than those for conventional irradiation.Synchronized irradiation with the authors' system allowed convenient and reliable reduction of the target volume. Further study is needed to standardize the system for clinical use.
- Subjects :
- Lung Neoplasms
Radiography
medicine.medical_treatment
Pilot Projects
Clinical Protocols
medicine
Humans
Radiology, Nuclear Medicine and imaging
Irradiation
Expiration
Lung cancer
Radiotherapy
business.industry
Pulse (signal processing)
Lasers
Patient Selection
Respiratory disease
Respiratory motion
Equipment Design
medicine.disease
Radiation therapy
Evaluation Studies as Topic
Respiratory Mechanics
Feasibility Studies
Particle Accelerators
business
Nuclear medicine
Subjects
Details
- ISSN :
- 15271315 and 00338419
- Volume :
- 207
- Database :
- OpenAIRE
- Journal :
- Radiology
- Accession number :
- edsair.doi.dedup.....221d4b428f990759e89656a8bcb9bafb