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A clinical evaluation of the Janus Web Application, a software screening tool for drug-drug interactions
- Source :
- European Journal of Clinical Pharmacology. 64:1209-1214
- Publication Year :
- 2008
- Publisher :
- Springer Science and Business Media LLC, 2008.
-
Abstract
- To evaluate the clinical relevance of the Janus Web Application (JWA) in screening for potential drug-drug interactions (DDIs). One hundred and fifty patients taking two drugs or more were studied. Potential DDIs were identified by the JWA. Interviewing the patient and looking into his/her medical records provided complementing information. A clinical pharmacologist judged which potential DDIs were clinically relevant. Potentially relevant DDIs identified by the JWA were then correlated with clinically relevant DDIs. A total of 150 significant potential DDIs were found. Sixteen percent (24/150) were judged to be clinically relevant. A very small proportion of DDIs was considered clinically relevant in the specific clinical context. To optimise the software’s user-friendliness, the following points need to be considered: the possibility of eliminating trivial potential DDIs, individualising drug alerts, and providing written information, accessible via a hyperlink.
- Subjects :
- Male
Drug
medicine.medical_specialty
Drug-Related Side Effects and Adverse Reactions
media_common.quotation_subject
Context (language use)
Pharmacology
Medical Records
law.invention
Drug Utilization Review
law
Surveys and Questionnaires
medicine
Humans
Web application
Drug Interactions
Pharmacology (medical)
Screening tool
Intensive care medicine
Aged
media_common
Sweden
Clinical pharmacology
business.industry
Medical record
General Medicine
Decision Support Systems, Clinical
medicine.disease
Pharmaceutical Preparations
Female
business
Clinical evaluation
Software
Adverse drug reaction
Subjects
Details
- ISSN :
- 14321041 and 00316970
- Volume :
- 64
- Database :
- OpenAIRE
- Journal :
- European Journal of Clinical Pharmacology
- Accession number :
- edsair.doi.dedup.....217842a8fec46d4505d666492b7f50ee