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Dietary supplementation with chestnut (Castanea sativa) reduces abdominal adiposity in FVB/n mice: A preliminary study
- Source :
- Biomedicines, Volume 8, Issue 4, Repositório Científico de Acesso Aberto de Portugal, Repositório Científico de Acesso Aberto de Portugal (RCAAP), instacron:RCAAP, Biomedicines, Vol 8, Iss 75, p 75 (2020)
- Publication Year :
- 2020
- Publisher :
- MDPI, 2020.
-
Abstract
- The production of chestnut (Castanea sativa Miller) is mostly concentrated in Europe. Chestnut is recognized by its high content of antioxidants and phytosterols. This work aimed to evaluate the effects of dietary chestnut consumption over physiological variables of FVB/n mice. Eighteen FVB/n male 7-month-old mice were randomly divided into three experimental groups (n = 6): 1 (control group) fed a standard diet<br />2 fed a diet supplemented with 0.55% (w/w) chestnut<br />and 3 supplemented with 1.1% (w/w) chestnut. Body weight, water, and food intake were recorded weekly. Following 35 days of supplementation, the mice were sacrificed for the collection of biological samples. Chestnut supplementation at 1.1% reduced abdominal adipose tissue. Lower serum cholesterol was also observed in animals supplemented with chestnut. There were no significant differences concerning the incidence of histological lesions nor in biochemical markers of hepatic damage and oxidative stress. These results suggest that chestnut supplementation may contribute to regulate adipose tissue deposition.
- Subjects :
- 0301 basic medicine
Food intake
Medicine (miscellaneous)
Adipose tissue
Biology
Body weight
medicine.disease_cause
General Biochemistry, Genetics and Molecular Biology
Article
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Animal science
Hepatic damage
In vivo
medicine
Dietary supplementation
lcsh:QH301-705.5
030109 nutrition & dietetics
Cholesterol
chemistry
lcsh:Biology (General)
Oxidative stress
030220 oncology & carcinogenesis
Standard diet
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Biomedicines, Volume 8, Issue 4, Repositório Científico de Acesso Aberto de Portugal, Repositório Científico de Acesso Aberto de Portugal (RCAAP), instacron:RCAAP, Biomedicines, Vol 8, Iss 75, p 75 (2020)
- Accession number :
- edsair.doi.dedup.....2160138c99e741ac1852f53cedbc7936