Back to Search
Start Over
Primary malignant melanoma of the uterine cervix: two case reports and a century's review
- Source :
- Obstetricalgynecological survey. 45(11)
- Publication Year :
- 1990
-
Abstract
- Primary malignant cervical melanoma is diagnosed by the presence of junctional melanocytic abnormality and the absence of distant metastasis. Amelanotic and poorly differentiated tumors can often be diagnosed with the HMB-45 immunoperoxidase stain which is very specific for melanoma. Early reported cases were treated with simple excision followed many times by radiation therapy. Radical hysterectomy, pelvic lymphadenectomy, and partial vaginectomy have been advocated by some contemporary investigators. Radiation can be used as adjuvant or palliative treatment; its efficacy is not well established. Few patients have been treated with modern chemotherapy. No patient has been treated with immunotherapy. Primary malignant cervical melanoma carries a very poor prognosis. Most patients succumb from their disease within 2 years. One patient has survived 14 years. The small number of reported cases makes it difficult to evaluate the efficacy of any treatment modality.
- Subjects :
- Oncology
Adult
medicine.medical_specialty
medicine.medical_treatment
Uterine Cervical Neoplasms
Disease
Internal medicine
medicine
Humans
Radical Hysterectomy
Melanoma
Chemotherapy
Immunoperoxidase
business.industry
Obstetrics and Gynecology
Vaginectomy
General Medicine
Middle Aged
medicine.disease
Prognosis
Radiation therapy
Female
Radiology
Cervical Melanoma
business
Subjects
Details
- ISSN :
- 00297828
- Volume :
- 45
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- Obstetricalgynecological survey
- Accession number :
- edsair.doi.dedup.....20d24bc5be58d70ff71f1478cf771bfe